| 乔 婕,李智敏,段昌虎,黄建玲,吕 杰.腹腔镜微创技术联合频谱照射治疗小儿阑尾炎的疗效及对血清slCAM-1、PCT水平的影响[J].,2020,(10):1952-1955 |
| 腹腔镜微创技术联合频谱照射治疗小儿阑尾炎的疗效及对血清slCAM-1、PCT水平的影响 |
| Efficacy of Laparoscopic Minimally Invasive Technology Combined with Spectrum Irradiation in the Treatment of Appendicitis in Children and the Influence on Serum slCAM-1 and PCT Levels |
| 投稿时间：2020-01-03 修订日期：2020-01-27 |
| DOI：10.13241/j.cnki.pmb.2020.10.034 |
| 中文关键词: 腹腔镜微创技术 频谱照射 小儿阑尾炎 肠功能恢复 可溶性细胞间粘附分子1 降钙素原 |
| 英文关键词: Laparoscopic minimally invasive technique Spectrum irradiation Appendicitis in children Intestinal function recovery Soluble intercellular adhesion molecule 1 Procalcitonin |
| 基金项目:陕西省科技攻关项目(2014k11-01-02-15) |
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| 中文摘要: |
| 摘要 目的：研究腹腔镜微创技术联合频谱照射治疗小儿阑尾炎的疗效及对血清可溶性细胞间粘附分子1(Soluble intercellular adhesion molecule-1，slCAM-1)、降钙素(Calcitonin，PCT)水平的影响。方法：选取2016年2月～2018年2月我院收治的87例小儿阑尾炎患者。按照简单随机数表法将其分为观察组(n=42)和对照组(n=45)，对照组采用传统手术治疗，观察组采用腹腔镜微创技术联合频谱照射治疗。观察和比较两组治疗后手术指标(手术时间、术中出血量、住院时间)，肠功能恢复情况(肠鸣音恢复时间、肛门排气时间、首次排便时间)，治疗前后血清slCAM-1、PCT水平的变化及不良反应的发生情况。结果：治疗后，观察组手术时间、术中出血量、住院时间显著低于对照组［(47.82±8.33)min vs (56.97±10.46)min，(46.97±9.75)mL vs (90.72±13.86)mL，(7.02±2.41)d vs (11.84±3.58)d］(P＜0.05)；肠鸣音恢复时间、肛门排气时间、首次排便时间显著低于对照组［(19.38±4.32)h vs (25.82±6.18)h，(16.98±4.59)h vs (36.83±7.29)h，(32.02±5.82)h vs (40.17±7.60)h］(P＜0.05)；血清slCAM-1、PCT水平显著低于对照组［(180.27±23.75)ng/L vs (197.06±27.30)ng/L(0.92±0.20)ng/L vs (3.87±1.03)ng/L］(P＜0.05)；不良反应总发生率显著低于对照组［7.14％(3/42) vs 22.22％(10/45)］(P＜0.05)。结论：腹腔镜微创技术联合频谱照射治疗小儿阑尾炎疗效显著，可改善微循环，促进肠功能恢复，降低血清slCAM-1、PCT水平，并发症少，有利于术后恢复。 |
| 英文摘要: |
| ABSTRACT Objective: To study the efficacy of laparoscopic minimally invasive technology combined with spectrum irradiation in the treatment of appendicitis in children and its influence on the serum soluble intercellular adhesion molecule-1(slCAM-1) and calcitonin(PCT) levels. Methods: 87 children with appendicitis who received therapy from February 2016 to February 2018 in our hospital were selected as research objects. According to random number table, those patients were divided into the observation group(n=42) and the control group(n=45). The control group was treated with traditional surgery, while the observation group treated with laparoscopic minimally invasive technique combined with spectral irradiation. The operation indexes (operation time, intraoperative bleeding volume, hospitalization time), intestinal function recovery(recovery time of bowel sounds, anal exhaust time, first defecation time), changes of serum slCAM-1, PCT level and incidence of adverse reactions were compared before and after treatment between the two groups. Results: After treatment, the operation time, intraoperative bleeding volume and hospitalization time in the observation group were significantly lower than those in the control group［(47.82±8.33)min vs (56.97±10.46)min, (46.97±9.75)mL vs (90.72±13.86)mL, (7.02±2.41)d vs (11.84±3.58)d］(P＜0.05). The recovery time of bowel sounds, anal exhaust time and first defecation time in the control group were significantly lower than those in the control group［(19.38±4.32)h vs (25.82±6.18)h, (16.98±4.59)h vs (36.83±7.29)h，(32.02±5.82)h vs (40.17±7.60)h］(P＜0.05). The levels of serum slCAM-1 and PCT were significantly lower than those in the control group［(180.27±23.75) ng/L vs (197.06±27.30), (0.92±0.20)ng/L vs (3.87±1.03)ng/L］(P＜0.05). The total incidence of adverse reactions was significantly lower than that in the control group［7.14%(3/42) vs 22.22%(10/45)］(P＜0.05). Conclusion: Laparoscopic minimally invasive technology combined with spectrum irradiation has a significant effect in the treatment of appendicitis in children. It can improve microcirculation, promote the recovery of intestinal function, reduce the level of serum slCAM-1 and PCT, and reduce complications, which is conducive to postoperative recovery. |
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