| 赵剑陈玉兰王桥黄锐杨光华.桂黄降脂颗粒质量标准研究*[J].,2014,14(15):2952-2955 |
| 桂黄降脂颗粒质量标准研究* |
| Study on The Quality Standard of Guihuang Jiangzhi Grain* |
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| DOI： |
| 中文关键词: 薄层色谱法 HPLC法 槲皮素 丹参素钠 质量标准 |
| 英文关键词: TLC HPLC Quercetin Sodiumdanshensu Quality Standard |
| 基金项目:四川省泸州市科技局中医药研究基金项目(20110315) |
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| 中文摘要: |
| 摘要目的：建立桂黄降脂颗粒的质量标准。方法：采用薄层色谱法对桂黄降脂颗粒中山楂、丹参进行定性鉴别；采用HPLC法对
山楂中的槲皮素和丹参中的丹参素钠进行含量测定。结果：薄层色谱斑点清晰、分离度效果较好、且阴性无干扰；槲皮素在11.2～
33.6 μg 范围内呈良好的线性关系，r =0.9995（n=5），样品平均回收率为98.00%，RSD 1.33%；丹参素钠在0.0166～0.332 mg·mL-1
范围内呈良好的线性关系，r =0.9998（n=5），样品平均回收率为97.87%，RSD 1.35%。结论：该方法准确可靠、专属性强、重现性
好，可以作为控制桂黄降脂颗粒质量的有效方法。 |
| 英文摘要: |
| ABSTRACT Objective:To establish the quality standard of Guihuang Jiangzhi Grain.Methods: TLC method was used to identify
Hawthor, Salvia miltiorrhiza ;HPLC method was used to quantitatively analyze the concentration of quercetin and sodium danshensu in
the Grain.Results: The TLC spots were clear without interference of the negative control. The linear range of quercetin was 11.2～33.6
μg, r=0.9995（n=5）, with the average recovery of 98.00%RSD 1.33%. The linear range of sodium danshensu was 0.0166～0.332 mg·
mL-1, r=0.9998 （n=5）, with the average recovery of 97.87% RSD 1.35%. Conclusion:The method is accurate, reliable, specific and
reproducible, and it can be used for the quality control of Guihuang Jiangzhi Grain. |
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