| 叶斌李文娟.微栓子监测及其在缺血性脑血管病中的应用研究进展[J].,2012,12(16):3191-3193 |
| 微栓子监测及其在缺血性脑血管病中的应用研究进展 |
| Monitoring and Microemboli in Ischemic Cerebrovascular Diseasein the Application of Research |
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| DOI： |
| 中文关键词: 超声检查 多普勒 经颅 微栓子 缺血性 |
| 英文关键词: Ultrasonography Doppler Transcranial Microemboli Ischemic |
| 基金项目: |
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| 中文摘要: |
| 微栓子监测技术（Microemboli monitoring technology，MMT）是20 世纪90 年代发展起来的一项新技术。1990 年，Spencer 等
定义了微栓子信号(Micro embolus signal，MES)。1992 年，Russell 等明确提出了微栓子监测的概念，并结合实验数据，对微栓子的
监测进行了初步总结。1995 年，第九届国际脑血流动力学会议确定了MES 的判断标准。近年来，微栓子监测技术已经广泛应用于
心脏、血管外科和神经科领域，并取得了一些进展。目前，不仅在理论上证实了应用TCD 技术监测微栓子的可行性，而且大量的
临床观察表明这项技术可以为研究缺血性脑血管病的发生机制、治疗效果、预后判断及疾病预防提供客观的依据。本文将对下述
问题进行综述：微栓子监测在缺血性脑血管病研究中的应用（颈源性、颅内动脉源性、心源性、其他病因所导致的缺血性脑血管
病）；微栓子监测对缺血性脑血管病药物治疗疗效的评估；微栓子监测对卒中复发的预计；以及微栓子监测对临床缺血性脑血管
病溶栓治疗的监测。综述近年来微栓子监测在临床缺血性脑血管病诊治预防中取得的新进展、面临的问题以及新的发展。 |
| 英文摘要: |
| Microemboli monitoring technology (MMT) in the 1990s developed a new technology. In 1990, Spencer and others
gave the definition of micro-embolic signals (Micro embolus signal, MES). In 1992, Russell and others clearly put forward the concept of
micro-emboli monitoring, and conducted a preliminary summary of the MMT on the basis of the experimental data. In 1995, the Ninth
International Cerebral Hemodynamics meeting identified criteria of MES. In recent years, micro-emboli monitoring technology (MMT)
has been widely used in cardiac, vascular surgery and neurology field, and has made some progress. Currently, not only application of
TCD technology to monitor the feasibility of micro-emboli were confirmed in theory, but also a large of clinical observations show that
MMT can provide an objective basis in order to study the occurrence, treatment, prognosis and prevention of ischemic cerebrovascular
disease. This paper will review the following issues: MMT in ischemic cerebrovascular disease research applications (cervical, intracranial
arterial origin, cardiac, and other causes resulting from ischemic cerebrovascular disease); MMT assessment ischemic cerebrovascular
disease therapy; MMT used to predict the recurrence of stroke; and MMT for monitoring clinical thrombolytic therapy of ischemic
cerebrovascular disease. This article will review the new progress, the new problems and new developments of MMT in the clinical
diagnosis, treatment and prevention of ischemic cerebrovascular disease in recent years. |
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