闫凤1 陈压西2 赵长海1.慢性炎症与动脉粥样硬化关系的研究进展[J].,2011,11(20):3964-3967 |
慢性炎症与动脉粥样硬化关系的研究进展 |
Progress of Chronic Systemic Inflammation and Atherosclerosis |
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DOI: |
中文关键词: 炎症 动脉粥样硬化 炎症介质 |
英文关键词: Inflammation atherosclerosis inflammatory mediator |
基金项目:国家自然科学基金(No.30871159,30971389,30772295,重点项目No.30530360),
重庆市自然科学基金重点项目(CSTC,2008BA5016) |
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中文摘要: |
动脉粥样硬化(atherosclerosis, AS)的发病机制非常复杂,对其研究经历了一个半世纪,直到1999 年Ross 提出" 动脉粥样
硬化是一种炎症性疾病",各种炎症细胞和炎症因子参与动脉粥样硬化的发生和发展过程。已有众多的基础和临床研究都证实炎
症在AS 中的重要作用,但仍需要对AS 发生发展的深入研究,使我们更准确认识和有效的防治AS。本文就近年来慢性炎症与动
脉粥样硬化关系的研究进展作一综述。 |
英文摘要: |
The pathogenesis of atherosclerosis (AS) which has been researched more than one and half centuries is extremely
complicated. Until 1999, Ross stated that "atherosclerosis is an inflammatory disease", various kinds of inflammatory cells and factors
took part in the progression of occurrence and development. There are many basic and clinical researches have demonstrated the
important role of inflammation in AS, but more lucubrates are needed for exactly recognition and effective prevention and treatment of
AS. This review summarizes the new progression of the relation between chronic systemic inflammation and atherosclerosis. |
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