| 宁宇王健.MicroRNA 与胶质瘤的分子病理特征研究进展[J].,2011,11(5):989-991 |
| MicroRNA 与胶质瘤的分子病理特征研究进展 |
| Progresses in MicroRNA and Features of Molecular Pathology of Glioma |
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| DOI： |
| 中文关键词: MicroRNA 胶质瘤 分子病理 基因 |
| 英文关键词: MicroRNA glioma Molecular Pathology gene |
| 基金项目: |
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| 中文摘要: |
| MicroRNAs(miRNAs)是一类非编码的内源性小RNA 分子，通过调节mRNA 的稳定性及蛋白翻译过程控制基因表达，从而
发挥促癌或抑癌作用；研究表明，在胶质瘤的发生、进展、侵袭过程中，伴随发生了许多分子病理特征的改变，这一过程中miRNAs
发挥着重要作用，本文就此方面研究进展进行综述。 |
| 英文摘要: |
| MicroRNAs(miRNAs) is a kind of non-coding endogenous small RNA molecules, which controls gene expression by
modulating the stabilities of mRNA and the progression of protein translation, and plays a role in tumor promotion or inhibition; studies
show that features of the molecular pathology of glioma change a lot in the progress of tumor genesis,progression and invasion, in which
miRNAs play an important role, this article reviewed the progresses of the research that concerned. |
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