| 滕光寿△1 刘曼玲2 毛峰峰3 韩燕1 杨鹏1 石磊1 畅敏1.小茴香挥发油的抗炎镇痛作用[J].,2011,11(2):344-346 |
| 小茴香挥发油的抗炎镇痛作用 |
| Anti-inflammatory and Analgesic Effects of Volatile Oil Extracted fromFoeniculum vulgare Mill. Seeds |
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| DOI： |
| 中文关键词: 小茴香 挥发油 抗炎 镇痛 |
| 英文关键词: Foeniculum vulgare Mill. Seeds Volatile oil Anti-inflammation Analgesia |
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| 中文摘要: |
| 目的：研究小茴香挥发油的抗炎、镇痛作用，为指导临床合理用药提供科学依据。方法：应用二甲苯致小鼠耳廓肿胀、蛋清致
大鼠足肿胀2 种动物模型进行抗炎药效学实验；采用醋酸致小鼠扭体反应进行镇痛实验。结果：小茴香挥发油能显著抑制上述各
种动物模型的炎症反应及醋酸引起的小鼠扭体反应。结论：小茴香挥发油具有抗炎和镇痛作用。 |
| 英文摘要: |
| Objective: To study the efects of anti-inflammatory and analgesic of volatile oil extracted from Foeniculum vulgare
Mill. Seeds and offer pharmacological and experimental basis for its safe and effective use in clinic．Methods: The pharmacodynamic
effects were obsersed in three experimental models of inflammation and pain：(1)mouse auricular edema induced by xylen；(2) Feet
tumefaction caused by albumen in rats；(3)writhing induced by acetic acid in mice. Results: Volatile oil from Foeniculum vulgare Mill.
Seeds could distinctively i nhibit the inflammatory edema caused by various inflammatory agents and reduce the times of writhe induced
by acetic acid in mice. Conclusion: Volatile oil from Foeniculum vulgare Mill. Seeds has analgesic effect and could inhibit inflammation
in animals. |
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