| Objective: To observe the clinical efficacy of repetitive transcranial magnetic stimulation (rTMS) combine with mindfulness-based cognitive therapy (MBCT) in patients with alcohol dependence withdrawal syndrome (AWS). Methods: The 120 patients with AWS who were observed in this study were all male patients admitted to our department from June 2021 to June 2024, the patients were divided into Group A (conventional treatment, 40 cases), Group B (group A combined with rTMS, 40 cases), and group C (Group B combined with MBCT, 40 cases) according to random number table method. The clinical efficacy, self-control ability [Modified Clinical Institution Alcohol Dependence Withdrawal Assessment Scale (CIWA-Ar) score, Visual Analog Scale of Psychological Craving for Alcohol (VAS) score and Pennsylvania Alcohol Craving Scale (PACS) score], anxiety and depression degree assessment [Hamilton Depression Scale (HAMD) score, Hamilton Anxiety Scale (HAMA) score] and quality of life assessment [36 Short Form Health Survey (SF-36) Score], relapse rate and readmission rate were compared among the three groups. Results: The total effective rate of group A, group B and group C increased successively (P<0.05). The CIWA-Ar, PACS and VAS scores in group B and group C after treatment were lower than those in group A, and group C was lower than that in group B (P<0.05). The HAMD and HAMA scores of group B and group C after treatment were lower than those in group A, and group C was lower than that in group B (P<0.05). The SF-36 score of group B and group C after treatment was higher than those in group A, and group C was higher than that in group B (P<0.05). Relapse rate and readmission rate in groups B and C were lower than those in group A, and group C was lower than that in group B (P<0.05). Conclusion: The application of rTMS combine with MBCT in AWS patients can improve clinical efficacy and quality of life, alleviate anxiety and depression, improve patients'' self-control ability, reduce relapse rate and readmission rate, with definite effects. |
