| 党 举,张志强,刘 超,韩 冰,王 颜.肌电生物反馈疗法联合温阳通络针灸对痉挛型脑瘫患儿脑血流动力学和血清神经因子的影响[J].现代生物医学进展英文版,2024,(15):2974-2978. |
| 肌电生物反馈疗法联合温阳通络针灸对痉挛型脑瘫患儿脑血流动力学和血清神经因子的影响 |
| Effects of Electromyographic Biofeedback Therapy Combined with Wenyang Tongluo Acupuncture on Cerebral Hemodynamics and Serum Nerve Factors in Children with Spastic Cerebral Palsy |
| Received:February 07, 2024 Revised:February 28, 2024 |
| DOI：10.13241/j.cnki.pmb.2024.15.033 |
| 中文关键词: 肌电生物反馈疗法 温阳通络针灸 痉挛型脑瘫 脑血流动力学 神经因子 |
| 英文关键词: Electromyographic biofeedback therapy Wenyang tongluo acupuncture Spastic cerebral palsy Cerebral hemodynamics Nerve factors |
| 基金项目:陕西省中医药管理局项目（2021-ZZ-LC002） |
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| 中文摘要: |
| 摘要 目的：观察肌电生物反馈疗法联合温阳通络针灸对痉挛型脑瘫患儿脑血流动力学和血清神经因子的影响。方法：按随机数字表法将西安中医脑病医院2021年4月至2023年5月期间收治的135例痉挛型脑瘫患儿分为对照组和联合组，分别为67例和68例。对照组接受肌电生物反馈疗法，联合组在对照组基础上接受温阳通络针灸。对比两组痉挛情况、运动情况、平衡功能、下肢肌力、脑血流动力学和血清神经因子。结果：联合组治疗3个月后痉挛情况改善效果优于对照组（P<0.05）。联合组治疗3个月后粗大运动功能评估表（GMFM）、Berg平衡量表（BBS）评分高于对照组（P<0.05）。联合组治疗3个月后髋关节外展肌力、膝关节屈肌力、膝关节伸肌力高于对照组（P<0.05）。联合组治疗3个月后动脉收缩期峰流速度、平均血流速度高于对照组，血管搏动指数、血管阻力指数低于对照组（P<0.05）。联合组治疗3个月后两组神经生长因子（NGF）、脑源性神经营养因子（BDNF）高于对照组（P<0.05）。结论：温阳通络针灸和肌电生物反馈疗法联合治疗痉挛型脑瘫患儿，可有效改善痉挛情况，提高下肢肌力和平衡功能，同时还可改善机体的脑血流动力学和血清神经因子水平。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effect of electromyographic biofeedback therapy combined with Wenyang tongluo acupuncture on cerebral hemodynamics and serum nerve factors in children with spastic cerebral palsy. Methods: 135 children with spastic cerebral palsy admitted to Xi'an TCM Hospital of Encephalopathy from April 2021 to May 2023 were divided into control group and combined group according to the random number table method, 67 cases and 68 cases respectively. Control group received electromyographic biofeedback therapy, and combined group received Wenyang tongluo acupuncture on the basis of control group. The spasm, movement, balance function, lower limb muscle strength, cerebral hemodynamics and serum nerve factors were compared between two groups. Results: The improvement of spasm condition in combined group was better than that in control group 3 months after treatment (P<0.05). The scores of Gross Motor Function Measure (GMFM) and Berg Balance Scale (BBS) in combined group were higher than those in control group 3 months after treatment (P<0.05). The abductor strength of hip joint, flexor strength of knee joint and extensor strength of knee joint in combined group were higher than those in control group 3 months after treatment (P<0.05). The arterial systolic peak flow velocity and mean blood flow velocity in combined group were higher than those in control group, and the vascular pulsatility index and vascular resistance index were lower than those in control group 3 months after treatment (P<0.05). The nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in combined group were higher than those in control group 3 months after treatment (P<0.05). Conclusion: The combination of wenyang tongluo acupuncture and electromyographic biofeedback therapy in the treatment of children with spastic cerebral palsy, which can effectively improve the spasm, improve the muscle strength and balance function of lower limbs, and improve the cerebral hemodynamics and serum nerve factor levels of the body. |
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