| 王双双,邝美丽,刘聪瑞,那 利,朱江伟.胸腔闭式引流管联合高频振荡通气对新生儿胎粪吸入综合征合并呼吸衰竭的应用效果分析[J].现代生物医学进展英文版,2024,(15):2970-2973. |
| 胸腔闭式引流管联合高频振荡通气对新生儿胎粪吸入综合征合并呼吸衰竭的应用效果分析 |
| Analysis of the Application Effect of Closed Thoracic Drainage Tube Combined with High-frequency Oscillatory Ventilation on Neonatal Meconium Aspiration Syndrome Complicated with Respiratory Failure |
| Received:January 08, 2024 Revised:January 28, 2024 |
| DOI：10.13241/j.cnki.pmb.2024.15.032 |
| 中文关键词: 胸腔闭式引流 高频振荡通气 新生儿胎粪吸入综合征 呼吸衰竭 |
| 英文关键词: Closed thoracic drainage High frequency oscillation ventilation Neonatal meconium aspiration syndrome Respiratory failure |
| 基金项目:国家卫生健康委医药卫生科技发展研究中心项目（WA2020HK41） |
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| 中文摘要: |
| 摘要 目的：探讨胸腔闭式引流管联合高频振荡通气对新生儿胎粪吸入综合征合并呼吸衰竭的应用效果。方法：选取我院2018年1月到2024年1月收治的60例胎粪吸入综合征合并呼吸衰竭新生儿，分为观察组与对照组，各30例。对照组患儿采取常规机械通气与胸腔闭式引流，观察组患儿采取胸腔闭式引流管联合高频振荡通气，对比相关指标。结果：与对照组相比，观察组治疗总有效率高（P＜0.05）；治疗前，两组患儿pH值、PaCO2、SaO2、PaO2水平对比无明显差异（P＞0.05），治疗后，两组患儿PaCO2降低，pH值、SaO2、PaO2升高，观察组与对照组比较有相同趋势（P＜0.05）；治疗前，两组患儿MAP、HR对比无明显差异（P＞0.05），治疗后两组患儿MAP升高，观察组高于对照组，HR降低，观察组低于对照组（P＜0.05）；两组患儿并发症发生率对比无差异（P＞0.05）。结论：胎粪吸入综合征合并呼吸衰竭且出现气胸的新生儿采取胸腔闭式引流管联合高频振荡通气可提升其临床疗效，改善其血气指标，稳定生命体征，且安全性较高。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the application effect of closed thoracic drainage tube combined with high-frequency oscillatory ventilation on neonatal meconium aspiration syndrome with respiratory failure. Methods: Sixty newborns with meconium aspiration syndrome and respiratory failure admitted to our hospital from January 2018 to January 2024 were selected. They were divided into an observation group and a matched group, with 30 cases. Children in the matched group adopted conventional mechanical ventilation and chest closed drainage, and children in the children in the observation group adopted chest closed drainage tube combined with high-frequency oscillatory ventilation to compare relevant indicators. Results: The total response rate in the observation group was high compared with the matched group (P<0.05); Before treatment, there was no significant difference in the pH value, PaCO2, SaO2, and PaO2 levels between the two groups of children (P>0.05). Post-treatment, PaCO2 decreased, and pH, SaO2 and PaO2 increased in the two groups, with the same trend compared with the control group (P<0.05); There was no difference in MAP and HR between the two groups of children before and Post-treatment (P>0.05); There was no difference in the incidence of complications between the two groups of children (P>0.05); Before treatment, there was no difference in MAP and HR between the two groups of children (P>0.05). Post-treatment, the MAP of the two groups of children increased, and the observation group was higher than the matched group, while HR decreased. The observation group was higher than the matched group (P<0.05); There was no difference in the incidence of complications between the two groups of children (P>0.05). Conclusion: For newborns with meconium aspiration syndrome combined with respiratory failure and pneumothorax, the use of closed thoracic drainage combined with high-frequency oscillatory ventilation can improve clinical efficacy, improve blood gas indicators, stabilize vital signs, and have high safety. |
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