| 李 敏,回记芳,张岁改,罗 虹,牛亦睿.对比分析不同矫治方法对青少年正畸患者唾液趋化因子、龈沟液炎症因子表达及牙周健康的影响[J].现代生物医学进展英文版,2024,(10):1921-1925. |
| 对比分析不同矫治方法对青少年正畸患者唾液趋化因子、龈沟液炎症因子表达及牙周健康的影响 |
| Comparative Analysis of the Effects of Different Orthodontic Methods on the Expression of Salivary Chemokines, Gingival Crevicular Fluid Inflammatory Factors, and Periodontal Health in Adolescent Orthodontic Patients |
| Received:November 15, 2023 Revised:December 11, 2023 |
| DOI：10.13241/j.cnki.pmb.2024.10.025 |
| 中文关键词: Twin-Block矫治器 直丝弓矫治器 无托槽隐性矫治器 唾液趋化因子 龈沟液炎症因子 牙周健康 |
| 英文关键词: Twin Block appliance Straight wire arch appliance Implicit orthodontic appliances without brackets Salivary chemokines Inflammatory factors in gingival crevicular fluid Periodontal health |
| 基金项目:陕西省重点研发计划一般项目社会发展领域（2022SF-281） |
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| 中文摘要: |
| 摘要 目的：对比分析不同矫治方法对青少年正畸患者唾液趋化因子、龈沟液炎症因子表达及牙周健康的影响。方法：选取我院2020年1月到2023年1月收治的100例正畸治疗的青少年患者，应用随机数字表法将其进行回顾性分析，其中30例患者采取Twin-Block矫治器进行治疗，将其分为Twin-Block组，30例患者采取直丝弓矫治器治疗，将其分为直丝弓组，40例患者采取无托槽隐性矫治器治疗，将其分为无托槽组。对比三组患者的矫正满意度，治疗前后唾液趋化因子、龈沟液炎症因子及牙周健康指标水平变化。结果：无托槽组咀嚼功能、美观程度、舒适性、方便程度满意度评分高于Twin-Block组和直丝弓组（P＜0.05）；矫治半年后，无托槽组CXCL13、CXCL11、CXCL10、CXCL8相关唾液趋化因子水平低于直丝弓组和Twin-Block组，Twin-Block组低于直丝弓组（P＜0.05）；三组患者矫治半年后，无托槽组IL-1β、TNF-α表达水平低于直丝弓组和Twin-Block组，Twin-Block组低于直丝弓组（P＜0.05）；矫治半年后，无托槽组CAL、PD、BI、PLI水平低于直丝弓组和Twin-Block组，Twin-Block组低于直丝弓组（P＜0.05）。结论：无托槽隐性矫治器在青少年正畸治疗患者满意度优于Twin-Block矫治器和直丝弓矫治器，但无托槽隐性矫治器治疗过程中对患者唾液趋化因子、牙龈雅正反应及牙周健康水平影响较小，临床可依照患者经济情况及对美观程度的要求综合选择。 |
| 英文摘要: |
| ABSTRACT Objective: To compare and analyze the effects of different orthodontic methods on the expression of salivary chemokines, gingival crevicular fluid inflammatory factors, and periodontal health in adolescent orthodontic patients. Methods: A total of 100 adolescent patients treated with orthodontic treatment in our hospital from January 2020 to January 2023 were selected. A retrospective analysis was conducted using a random number table method. Among them, 30 patients were treated with Twin Block appliances and divided into a Twin Block group. 30 patients were treated with a straight wire appliance and divided into a straight wire arch group. 40 patients were treated with a non bracket concealed appliance and divided into a non bracket group. Compare the corrective effects of three groups of patients, including changes in salivary chemokines, gingival crevicular fluid inflammatory factors, and periodontal health indicators before and after treatment. Results: Masticatory function, aesthetics, comfort, and convenience satisfaction scores were higher than those in the Twin-Block and straight silk arch groups(P<0.05); After the correction correction, The levels of CXCL13, CXCL11, CXCL10, and CXCL 8 related salivary chemokines in the no-bracket group were lower than those in the straight and Twin-Block groups, The Twin-Block group was lower than the straight silk arch group(P<0.05); After the correction in the three groups of patients, The expression levels of IL-1β and TNF-α in the no-free group were lower than the straight filament arch group and Twin-Block group, The Twin-Block group was lower than the straight silk arch group (P<0.05); After the correction correction, CAL, PD, BI and PLI levels were lower in the no less group than in the straight silk arch and Twin-Block group, The Twin-Block group was lower than that in the straight silk arch group (P<0.05). Conclusion: Invisible bracketless orthodontic appliances in adolescent orthodontic treatment patient satisfaction is better than Twin-Block orthodontic appliances and straight arch orthodontic appliances, but invisible bracketless orthodontic appliances in the treatment process of the patient's salivary chemokines, gingival response and periodontal health level of the impact of less, the clinic can be in accordance with the patient's economic situation and the degree of aesthetics of the requirements of a comprehensive choice. |
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