| 王艳妮,桑 琳,吕发辉,张 莉,丁玉芹.妇炎消胶囊联合头孢地尼胶囊对慢性盆腔炎患者血液流变学和血清炎性因子的影响[J].现代生物医学进展英文版,2024,(7):1349-1352. |
| 妇炎消胶囊联合头孢地尼胶囊对慢性盆腔炎患者血液流变学和血清炎性因子的影响 |
| Effects of Fuyanxiao Capsules Combined with Cefdinir Capsules on Hemorheology and Serum Inflammatory Factors in Patients with Chronic Pelvic Inflammatory Disease |
| Received:August 26, 2023 Revised:September 23, 2023 |
| DOI：10.13241/j.cnki.pmb.2024.07.029 |
| 中文关键词: 妇炎消胶囊 头孢地尼胶囊 慢性盆腔炎 血液流变学 炎性因子 |
| 英文关键词: Fuyanxiao capsules Cefdinir capsules Chronic pelvic inflammatory disease Hemorheology Inflammatory factors |
| 基金项目:安徽省高等学校省级质量工程项目（2017zhkt255） |
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| 中文摘要: |
| 摘要 目的：观察妇炎消胶囊联合头孢地尼胶囊对慢性盆腔炎患者血液流变学和血清炎性因子的影响。方法：选择2022年2月-2023年2月期间合肥市第二人民医院收治的慢性盆腔炎患者106例。按照双色球法将患者分为对照组和实验组，各为53例。对照组接受头孢地尼胶囊，实验组在对照组的基础上接受妇炎消胶囊，均治疗14天。对比两组疗效、临床症状缓解、炎症因子、血液流变学和不良反应。结果：实验组的临床总有效率高于对照组（P<0.05）。实验组的腹痛消失时间、白带异常消失时间短于对照组（P<0.05）。治疗后，实验组超敏C反应蛋白（hs-CRP）、血浆黏度值、钙素原（PCT）、红细胞聚集指数、白介素6（IL-6）、全血高切还原黏度、血清淀粉样蛋白（SAA）、全血低切还原黏度低于对照组（P<0.05）。两组不良反应发生率组间对比未见差异（P>0.05）。结论：妇炎消胶囊联合头孢地尼胶囊治疗慢性盆腔炎患者，可有效改善患者的临床症状，改善血液流变学，降低血清炎性因子水平，且无明显不良反应。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effects of fuyanxiao capsules combined with cefdinir capsules on hemorheology and serum inflammatory factors in patients with chronic pelvic inflammatory disease. Methods: 106 patients with chronic pelvic inflammatory disease who were admitted to the Hefei Second People's Hospital from February 2022 to February 2023 were selected. Patients were divided into control group and experimental group according to the two-color ball method, with 53 cases in each group. Control group received cefdinir capsules, and experimental group received fuyanxiao capsules on the basis of control group, and all patients were treated for 14 days. The efficacy, clinical symptom relief, inflammatory factors, hemorheology and adverse reactions were compared between two groups. Results: The total clinical effective rate in experimental group was higher than that in control group (P<0.05). The disappearance time of abdominal pain and leucorrhea abnormality in experimental group was shorter than that in control group(P<0.05). After treatment, the levels of high-sensitivity C-reactive protein (hs-CRP), plasma viscosity, procalcitonin (PCT), erythrocyte aggregation index, interleukin-6 (IL-6), whole blood high-shear reduced viscosity, serum amyloid protein (SAA) and whole blood low-shear reduced viscosity in experimental group were lower than those in control group(P<0.05). There was no difference in the incidence of adverse reactions between two groups(P>0.05). Conclusion: Fuyanxiao capsules combined with cefdinir capsules in the treatment of patients with chronic pelvic inflammatory disease, which can effectively improve the clinical symptoms of patients, improve hemorheology, reduce the level of serum inflammatory factors, and no obvious adverse reactions. |
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