| 刘 波,于依蕾,董小瑾,董宝杰,刘 妍.固本健脑安神方联合针灸对慢性失眠的治疗效果及对日间脑功能状态影响[J].现代生物医学进展英文版,2024,(3):459-463. |
| 固本健脑安神方联合针灸对慢性失眠的治疗效果及对日间脑功能状态影响 |
| Effect of Gubenjiannao Anshen Prescription Combined with Acupuncture on Chronic Insomnia and Its Influence on Daytime Brain Function |
| Received:June 21, 2023 Revised:July 16, 2023 |
| DOI：10.13241/j.cnki.pmb.2024.03.011 |
| 中文关键词: 固本健脑安神方 针灸 慢性失眠 效果 日间脑功能 |
| 英文关键词: Gubenjiannao Anshen prescription Acupuncture Chronic insomnia Effect Daytime brain function |
| 基金项目:国家中医药管理局全国名老中医药专家传承工作室建设项目（20220002） |
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| 中文摘要: |
| 摘要 目的：探讨固本健脑安神方联合针灸对慢性失眠的治疗效果及对日间脑功能状态影响。方法：选取我院于2021年1月份到2022年12月份期间收治的120例慢性失眠患者进行研究，根据患者就诊日期进行分组，其中60例奇数日期就诊的患者作为对照组（接受针灸治疗），另外60例偶数日期就诊的患者作为观察组（接受固本健脑安神方联合针灸治疗）。对比两组愈显率、总有效率、匹兹堡睡眠质量指数（PSQI）量表评分、日间失眠症状反应量表（DISS）评分、过度觉醒量表（HAS）评分、不良反应发生率、生活质量评价量表（SF-36）评分。结果：（1）观察组愈显率为71.67%，对照组愈显率为53.33%，观察组明显高于对照组（P＜0.05）；观察组总有效率为95.00%，对照组总有效率为83.33%，观察组明显高于对照组（P＜0.05）。（2）治疗前，对两组睡眠时间、入睡时间、睡眠质量、睡眠效率、日间功能障碍、睡眠障碍、睡眠药物评分以及总分进行对比（P＞0.05）；治疗后，两组上述评分均出现不同程度的降低，且观察组比对照组低（P＜0.05）。（3）治疗前，对两组DISS评分及HAS评分进行对比（P＞0.05）；治疗后，两组上述评分均出现不同程度的降低，且观察组比对照组低（P＜0.05）。（4）经过治疗，观察组出现恶心呕吐、头痛头晕、口苦、疲乏无力、肝肾功能异常等不良反应的概率为6.67%，对照组为3.33%，两组比较（P＞0.05）。（5）治疗前，对两组生活质量评分进行对比无差异（P＞0.05）；治疗后，评分升高，且观察组比对照组高（P＜0.05）。结论：固本健脑安神方联合针灸治疗慢性失眠可明显提升愈显率和总有效率，改善睡眠障碍情况，提高日间脑功能状态，同时改善过度觉醒状态，促使患者生活质量得以提高，且安全性较高。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the therapeutic effect of GubenJiannao Anshen prescription combined with acupuncture on chronic insomnia and its influence on daytime brain function. Methods: A total of 120 patients with chronic insomnia admitted to our hospital from January 2021 to December 2022 were selected for the study. The patients were divided into groups according to the admission date, and 60 patients admitted on odd date were used as the matched group (receiving acupuncture treatment). Another 60 patients admitted on even dates were used as observation group (receiving GubenJiannao Anshen prescription combined with acupuncture treatment). The apparent rate, total response rate, Pittsburgh sleep quality index (PSQI) score, daytime insomnia symptom scale (daytime insomnia symptom scale) score were compared between the two groups. DISS), hyperarousal scale (HAS), incidence of adverse reactions, and short form 36 questionnaire (SF-36). Results: (1) The apparent rate was 71.67% in the observation group and 53.33% in the matched group, which was higher than that in the matched group(P<0.05). The total effective rate was 95.00% in the observation group and 83.33% in the matched group, which was higher than that in the matched group (P<0.05). (2) Pretherapy, sleep time, sleeping time, sleep quality, sleep efficiency, daytime dysfunction, sleep disorders, sleep medication scores and total scores of the two groups were compared (P>0.05); Post-treatment, the above scores of the two groups were decreased to different degrees, and the observation group was lower than the matched group(P<0.05). (3) pretherapy, DISS scores and HAS scores of the two groups were compared (P>0.05); Post-treatment, the above scores of the two groups were decreased to different degrees, and the observation group was lower than the matched group (P<0.05). (4) Post-treatment, the probability of adverse reactions such as nausea, vomiting, headache, dizziness, bitter mouth, fatigue and weakness, abnormal liver and kidney function was 6.67% in the observation group and 3.33% in the matched group, compared between the two groups (P>0.05). (5) pretherapy, the quality of life scores of the two groups were compared (P>0.05); Post-treatment, the quality of life scores of both groups were increased to different degrees, and the observation group was higher than the matched group (P<0.05). Conclusion: GubenJiannao Anshen prescription combined with acupuncture and moxibustion in the treatment of chronic insomnia can significantly improve the discernibility and total effective rate, improve the sleep disorder, improve the daytime brain function, and improve the excessive awakening state, and promote the quality of life of patients with high safety. |
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