| 孙红梅,王骁智,张新月,徐冬梅,魏 岚,沈沭彤.基于老年综合评估结果指导治疗对老年冠心病患者心功能、脂代谢和生活质量的影响[J].现代生物医学进展英文版,2023,(22):4247-4251. |
| 基于老年综合评估结果指导治疗对老年冠心病患者心功能、脂代谢和生活质量的影响 |
| The Effects of Guidance Treatment Based on the Results of Comprehensive Geriatric Assessment on Cardiac Function, Lipid Metabolism and Quality of Life in Elderly Patients with Coronary Heart Disease |
| Received:May 04, 2023 Revised:May 28, 2023 |
| DOI：10.13241/j.cnki.pmb.2023.22.009 |
| 中文关键词: 老年综合评估结果 老年 冠心病 心功能 脂代谢 生活质量 |
| 英文关键词: Results of comprehensive geriatric assessment Elderly Coronary heart disease Cardiac function Lipid metabolism Quality of life |
| 基金项目:国家自然科学基金青年科学基金项目（81900356） |
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| 中文摘要: |
| 摘要 目的：探讨基于老年综合评估结果指导（CGA）治疗对老年冠心病患者心功能、脂代谢和生活质量的影响。方法：本次研究将2020年6月-2022年1月在江苏省人民医院心血管内科接受治疗的106例老年冠心病患者，采用随机数字法将其随机分为对照组（常规药物治疗，53例）与研究组（对照组的基础上结合CGA治疗，53例）。对比两组疗效、心功能、脂代谢和生活质量相关情况。结果：研究组的临床总有效率为94.34%，明显高于对照组的79.25%（P<0.05）。研究组治疗3个月后左心室舒张期末内径（LVEDD）、左心室收缩期末内径（LVESD）低于对照组，左心室射血分数（LVEF）高于对照组（P<0.05）。研究组治疗3个月后高密度脂蛋白胆固醇（HDL-C）高于对照组，甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）低于对照组（P<0.05）。研究组治疗3个月后病情、体力、医疗状况、一般生活、社会心理状况、工作状况各维度评分高于对照组（P<0.05）。研究组的住院期间心脏不良事件总发生率低于对照组（P<0.05）。结论：基于CGA治疗老年冠心病，可有效改善心功能、脂代谢，降低住院期间不良事件发生率，提高患者的生活质量。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effects of guidance treatment based on the results of comprehensive geriatric assessment (CGA) on cardiac function, lipid metabolism and quality of life in elderly patients with coronary heart disease. Methods: In this study, 106 elderly patients with coronary heart disease who received treatment in Department of Internal Medicine-Cardiovascular of Jiangsu Provincial People's Hospital from June 2020 to January 2022 were selected, and they were randomly divided into control group (conventional drug treatment, 53 cases) and study group (combined with CGA treatment on the basis of the control group, 53 cases) by random number method. Efficacy, cardiac function, lipid metabolism and quality of life were compared in the two groups. Results: The total clinical effective rate in the study group was 94.34%, which was significantly higher than 79.25% in the control group (P<0.05). 3 months after treatment, the left ventricular end-diastolic diameter (LVEDD) and the left ventricular end-systolic diameter (LVESD) in the study group were lower than those in the control group, and the left ventricular ejection fraction (LVEF) was higher than that in the control group (P<0.05). 3 months after treatment, the high density lipoprotein cholesterol (HDL-C) in the study group was higher than that in the control group, while the triglyceride (TG), total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) were lower than those in the control group (P<0.05). 3 months after treatment, the scores of illness, physical strength, medical condition, general life, social psychological condition and working condition dimensions in the study group were higher than those in the control group (P<0.05). The total incidence of cardiac adverse events during hospitalization in the study group was lower than that in the control group(P<0.05). Conclusion: The treatment of elderly coronary heart disease based on CGA can effectively improve cardiac function, lipid metabolism, and reduce the incidence of adverse events during hospitalization, and improve the quality of life of patients. |
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