| 沈永艳,范家权,沈 丽,赵 丽,李大苇.神经肌肉电刺激联合间歇性充气加压预防颅脑外伤患者下肢深静脉血栓的临床研究[J].现代生物医学进展英文版,2023,(19):3690-3694. |
| 神经肌肉电刺激联合间歇性充气加压预防颅脑外伤患者下肢深静脉血栓的临床研究 |
| Clinical Study of Neuromuscular Electrical Stimulation Combined with Intermittent Pneumatic Compression in Preventing Lower Extremity Deep Venous Thrombosis in Patients with Craniocerebral Trauma |
| Received:March 06, 2023 Revised:March 28, 2023 |
| DOI：10.13241/j.cnki.pmb.2023.19.018 |
| 中文关键词: 神经肌肉电刺激 间歇性充气加压 颅脑外伤 下肢深静脉血栓 临床疗效 |
| 英文关键词: Neuromuscular electrical stimulation Intermittent pneumatic compression Craniocerebral trauma Lower extremity deep venous thrombosis Clinical efficacy |
| 基金项目:安徽省红十字会中医药传承创新发展研究项目（2021ZYZD04） |
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| 中文摘要: |
| 摘要 目的：探讨神经肌肉电刺激（NMES）联合间歇性充气加压预防颅脑外伤患者下肢深静脉血栓（LEDVT）的临床疗效，为预防LEDVT干预措施的选择提供依据。方法：将2020年11月至2021年8月于安徽中医药大学附属六安医院就诊的72例颅脑外伤患者纳入研究对象，随机数字法分为对照组和观察组，各组36例。对照组给予常规措施+间歇性充气加压干预，观察组在对照组基础上联合NMES干预。收集患者资料，比较两组LEDVT情况、卧床时间、住院时间、干预前后凝血功能指标[凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、D-二聚体（D-D）及纤维蛋白原（FIB）]水平、腘静脉、股总静脉血液流速、视觉疼痛模拟量表（VAS）评分，日常生活能力量表（ADL）评分。结果：观察组LEDVT发生率5.56%（2/36）低于对照组25.00%（9/36），卧床时间、住院时间短于对照组（P＜0.05）；两组干预后凝血功能指标PT、APTT、D-D、FIB水平较干预前显著改善，且观察组较对照组改善更为显著（P＜0.05）；两组干预后腘静脉、股总静脉血液流速、ADL评分较干预前升高，VAS评分较干预前降低，且观察组腘静脉、股总静脉血液流速、ADL评分高于对照组，VAS评分低于对照组（P＜0.05）。结论：NMES联合间歇性充气加压干预能缩短颅脑外伤患者卧床时间和住院时间，改善患者凝血功能和血液循环，减少LEDVT的发生，且有助于减轻患者疼痛，提高患者生活能力。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinical efficacy of neuromuscular electrical stimulation(NMES) combined with intermittent pneumatic compression in the prevention of lower extremity deep venous thrombosis(LEDVT) in patients with craniocerebral trauma, and to provide evidence for the selection of intervention measures to prevent LEDVT. Methods: A total of 72 patients with craniocerebral trauma who were treated at the Lu'an Hospital Affiliated to Anhui University of Traditional Chinese Medicine from November 2020 to August 2021 were included in the study. They were randomly divided into control group and an observation group, with 36 patients in each group. The control group was given routine measures plus intermittent pneumatic compression intervention, while the observation group was given NMES based on the control group. Patient data were collected and compared between the two groups in terms of LEDVT status, length of bed, hospital stay,coagulation function indicators (prothrombin time (PT), activated partial thromboplastin time (APTT), D-dimer (D-D), and fibrinogen (FIB)) levels, blood flow velocity of popliteal vein and common femoral vein,Visual analogue scale (VAS) score, and activities of daily living (ADL) score before and after intervention. Results: The incidence of LEDVT in the observation group was 5.56% (2/36) lower than that 25.00% (9/36) in the control group, and the, length of bed and hospital stay in the observation group was shorter than that in the control group(P<0.05). After intervention, the levels of PT, APTT, D-D, FIB in the two groups were significantly improved compared to those before intervention, and the improvement in the observation group was more significant than that in the control group(P<0.05). After intervention, the blood flow velocity of popliteal vein and common femoral vein and ADL score in the two groups increased compared to those before intervention,while the VAS score decreased compared to those before intervention. The blood flow velocity of popliteal vein and common femoral vein and ADL score in the observation group were higher than those in the control group, while the VAS score were lower than those in the control group (P<0.05). Conclusion: NMES combined with intermittent pneumatic compression can shorten the bedtime and hospitalization time of patients with craniocerebral trauma, improve the coagulation function and blood circulation of patients, reduce the occurrence of LEDVT, and help to alleviate pain and improve their ability of live. |
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