| 王淑兰,张克珍,李雪翔,李 娟,代婷婷,毕清泉.术前降钙素原、血红蛋白、中性粒细胞与淋巴细胞比值与永久性心脏起搏器植入患者术后囊袋感染的关系研究[J].现代生物医学进展英文版,2023,(19):3678-3682. |
| 术前降钙素原、血红蛋白、中性粒细胞与淋巴细胞比值与永久性心脏起搏器植入患者术后囊袋感染的关系研究 |
| Relationship Study between Preoperative Procalcitonin, Hemoglobin, Neutrophil-to-lymphocyte Ratio and Postoperative Capsular Bag Infection in Patients with Permanent Pacemaker Implantation |
| Received:March 23, 2023 Revised:April 18, 2023 |
| DOI：10.13241/j.cnki.pmb.2023.19.016 |
| 中文关键词: 永久性心脏起搏器植入术 降钙素原 血红蛋白 中性粒细胞与淋巴细胞比值 囊袋感染 |
| 英文关键词: Permanent pacemaker implantation Procalcitonin Hemoglobin Neutrophil-to-lymphocyte ratio Capsular bag infection |
| 基金项目:安徽省高校自然科学研究项目（KJ2021ZD0026） |
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| 中文摘要: |
| 摘要 目的：探讨术前降钙素原（PCT）、血红蛋白（Hb）、中性粒细胞与淋巴细胞比值（NLR）与永久性心脏起搏器植入（PPI）患者术后囊袋感染的关系。方法：回顾性选取2019年7月～2021年7月安徽医科大学第二附属医院收治的400例PPI患者，根据术后1年是否发生囊袋感染分为感染组和非感染组。收集患者临床资料和术前PCT、Hb、NLR水平。采用单因素和多因素Logistic回归分析PPI患者术后囊袋感染的影响因素，采用受试者工作特征（ROC）曲线分析术前PCT、Hb、NLR对PPI患者术后囊袋感染的预测价值。结果：随访1年，400例PPI患者术后囊袋感染发生率为8.00%（32/400）。多因素Logistic回归分析显示，年龄增加、糖尿病、起搏器更换/升级、术后囊袋血肿和PCT、NLR升高、Hb降低为PPI患者术后囊袋感染的独立危险因素（P＜0.05）。ROC曲线分析显示，术前PCT、Hb、NLR联合预测PPI患者术后囊袋感染的曲线下面积大于PCT、Hb、NLR单独预测。结论：术前PCT、NLR升高和Hb降低与PPI患者术后囊袋感染有关，术前PCT、Hb、NLR联合预测术后囊袋感染的价值较高。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the relationship between preoperative procalcitonin (PCT), hemoglobin (Hb), neutrophil-to-lymphocyte ratio (NLR) and postoperative capsular bag infection in patients with permanent pacemaker implantation (PPI). Methods: 400 patients with PPI who were admitted to the Second Affiliated Hospital of Anhui Medical University from July 2019 to July 2021 were retrospectively selected, and they were divided into infected group and non-infected group according to whether capsular bag infection occurred 1 year after surgery. Clinical data and preoperative PCT, Hb and NLR levels of patients were collected. Univariate and multivariate Logistic regression were used to analyze the influencing factors of postoperative capsular bag infection in patients with PPI, and receiver operating characteristic (ROC) curve was used to analyze the predictive value of preoperative PCT, Hb and NLR for postoperative capsular bag infection in patients with PPI. Results: After 1-year follow-up, the incidence of postoperative capsular bag infection in 400 patients with PPI was 8.00% (32/400). Multivariate Logistic regression analysis showed that increased age, diabetes mellitus, pacemaker replacement/upgrade, postoperative capsular bag hematoma, elevated PCT and NLR, reduced Hb were independent risk factors for postoperative capsular bag infection in patients with PPI (P＜0.05). ROC curve analysis showed that the area under the curve of preoperative PCT, Hb and NLR combined prediction of postoperative capsular bag infection in patients with PPI was greater than that predicted by PCT, Hb and NLR alone. Conclusion: Preoperative PCT, elevated NLR and reduced Hb are associated with postoperative capsular bag infection in patients with PPI, and the combination of preoperative PCT, Hb and NLR is of high value in predicting postoperative capsular bag infection. |
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