| 陈 琦,唐晓敏,胡云龙,孙煦明,刘 成.不同听力曲线分型突发性耳聋患者听阈水平及临床特征分析[J].现代生物医学进展英文版,2023,(11):2113-2117. |
| 不同听力曲线分型突发性耳聋患者听阈水平及临床特征分析 |
| Analysis of Hearing Threshold and Clinical Characteristics of Patients with Sudden Deafness Classified by Different Hearing Curves |
| Received:January 10, 2023 Revised:January 31, 2023 |
| DOI：10.13241/j.cnki.pmb.2023.11.022 |
| 中文关键词: 不同听力曲线分型 突发性耳聋 听阈水平 临床特征分析 |
| 英文关键词: Different hearing curve classification Sudden deafness Hearing threshold level Analysis of Clinical Features |
| 基金项目:2019年度安徽省高校自然科学研究一般项目（ZR2019B02） |
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| 中文摘要: |
| 摘要 目的：探讨不同听力曲线分型突发性耳聋患者听阈水平及临床特征分析。方法：前瞻性选取我院2019年10月至2022年10月我院收治的80例突发性耳聋患者作为研究对象。采集患者临床特征信息。检测所有患者听阈水平。采用秩和检验进行多组间差异分析；采用Spearman检验进行相关性分析；采用多元线性回归模型进行回归分析。结果：平坦下降组、低频下降组、高频下降组和全聋组在侧别、性别、糖尿病、耳鸣、眩晕、耳闷胀感亚组间差异显著（P<0.05），而在年龄、高血压和脑梗塞亚组间无显著差异（P＞0.05）；平坦下降组、低频下降组、高频下降组和全聋组在极重度、重度、中度、轻度、正常亚组间差异显著（P<0.05）；突发性耳聋患者听力曲线分型与侧别、性别、糖尿病、耳鸣眩晕、耳闷胀感、听阈水平密切相关（P<0.05），而与年龄、高血压、脑梗塞无关（P＞0.05）；多元线性回归结果显示，耳鸣、眩晕、耳闷胀感、听阈水平、侧别是影响突发性耳聋患者听力曲线分型的独立危险因素（P<0.05）。结论：突发性耳聋不同听力曲线分型患者间存在临床特征及听阈水平的差异，临床可依据患者独特疾病特征构建精准的治疗策略进行干预。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the hearing threshold and clinical characteristics of patients with sudden deafness classified by different hearing curves. Methods: Prospectively, 80 patients with sudden deafness admitted to our hospital from October 2019 to October 2022 were selected as the study population. Information on the clinical characteristics of the patients was collected. The hearing threshold levels of all patients were tested. The rank sum test was used for the analysis of differences between multiple groups; the Spearman test was used for correlation analysis; and the multiple linear regression model was used for regression analysis. Results: There were significant differences between the flat drop group, low frequency drop group, high frequency drop group and total deafness group in terms of side, gender, diabetes, tinnitus, vertigo, and ear swelling sensation subgroups(P<0.05), but there were no significant differences among the age, hypertension and cerebral infarction subgroups(P>0.05). There were significant differences among the flat descending group, low frequency descending group, high frequency descending group and total deafness group in extremely severe, severe, moderate, mild and normal subgroups(P<0.05); Hearing curve typing in patients with sudden deafness is closely related to side, gender, diabetes, tinnitus vertigo, ear congestion, and hearing threshold level(P<0.05), but not related to age, hypertension and cerebral infarction (P>0.05). Multiple linear regression results showed that tinnitus, vertigo, ear stuffiness, hearing threshold level, and lateral discrimination were independent risk factors affecting hearing curve typing in patients with sudden deafness (P<0.05). Conclusion: There are differences in clinical characteristics and hearing thresholds among patients with different hearing profiles of sudden deafness, and clinical interventions can be constructed based on patients' unique disease characteristics. |
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