| 浩光东,樊 艳,丁小函,万玛草,姚银东,白 洁.二术二陈汤联合有氧运动、阻抗运动对2型糖尿病患者心肺功能、血糖控制效果的观察[J].现代生物医学进展英文版,2023,(9):1691-1695. |
| 二术二陈汤联合有氧运动、阻抗运动对2型糖尿病患者心肺功能、血糖控制效果的观察 |
| Observation of the Effect of Erchen Decoction Combined with Aerobic Exercise and Impedance Exercise on Cardiopulmonary Function and Blood Glucose Control in Patients with Type 2 Diabetes Mellitus |
| Received:October 05, 2022 Revised:October 28, 2022 |
| DOI：10.13241/j.cnki.pmb.2023.09.018 |
| 中文关键词: 二术二陈汤 氧运动 阻抗运动 2型糖尿病 心肺功能 |
| 英文关键词: Ershu Erchen Decoction Oxygen movement Impedance motion Type 2 diabetes mellitus Heart and lung function |
| 基金项目:国家自然科学基金青年基金项目（81801382） |
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| 中文摘要: |
| 摘要 目的：探究二术二陈汤联合有氧运动、阻抗运动对2型糖尿病患者心肺功能、血糖控制效果。方法：选择2017年5月~2022年7月本院收治的60例2型糖尿病患者为本次研究对象，随机数字表法分组，观察组，n=30，对照组，n=30。对照组进行基础治疗，对照组用药基础上，联合二术二陈汤+有氧及阻抗运动治疗观察组。比较心肺功能、血管内皮功能、血糖控制效果、不良反应。结果：治疗后，观察组舒张末期容积（EDV）、左室收缩末期容积（ESV）、内皮素-1（ET-1）显著低于对照组，而一氧化氮（NO）、内皮依赖性血管舒张功能（FMD）、1 s用力呼气容积（FEV1）、FEV1/FVC显著高于对照组（P＜0.05）；治疗后，空腹血糖（FBG）、餐后2 h血糖（2hPBG）、糖化血红蛋白（HbA1c）指标水平，与治疗前比较，观察组及对照组均降低，且观察组低于对照组（P＜0.05）；观察组不良反应率为20.00 %，对照组不良反应率为23.33 %，观察组与对照组比较无差异（P＞0.05）。结论：二术二陈汤联合有氧运动、阻抗运动可有效提升2型糖尿病患者心肺功能，改善血管内皮功能，降低血糖水平，且安全性较高。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the effects of Erchen Decoction combined with aerobic exercise and impedance exercise on cardiopulmonary function and blood glucose control in patients with type 2 diabetes. Methods: Sixty patients with type 2 diabetes admitted to our hospital from May 2017 to July 2022 were selected as the subjects of this study. They were divided into observation group (n=30) and control group (n=30) by random number table method. The control group was treated with basic therapy, and the control group was treated with the combination of Erjiao Er Chen Tang + aerobic and impedance exercise on the basis of medication for the observation group. Compare the cardiopulmonary function, vascular endothelial function, blood glucose control effect, and adverse reactions. Results: Post-treatment, end-diastolic volume (EDV), left ventricular end-systolic volume (ESV), and endothelin-1 (ET-1) were lower in the observation group than in the control group, while nitric oxide (NO), endothelium-dependent vasodilatory function (FMD), 1 s forceful expiratory volume (FEV1), and FEV1/FVC were higher than in the control group (P<0.05). Post-treatment, fasting blood glucose (FBG), 2 h postprandial blood glucose (2hPBG) and glycosylated hemoglobin (HbA1c) index levels in observation group and control group were decreased compared with pre-treatment, and observation group was lower than control group (P<0.05). The adverse reaction rate was 20.00 % and 23.3 3% in the control group, with no difference between the observation group and the control group (P>0.05). Conclusion: Erchen Decoction combined with aerobic exercise and impedance exercise can effectively improve the cardiopulmonary function, vascular endothelial function and blood glucose level in patients with type 2 diabetes, with high safety. |
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