| 闫文雪,任 玲,方娅霞,葛正懿,李珊珊.低频脉冲刺激穴位疗法联合规律有氧运动对2型糖尿病周围神经病变患者感觉阈值、神经传导速度和血液流变学的影响[J].现代生物医学进展英文版,2023,(4):761-765. |
| 低频脉冲刺激穴位疗法联合规律有氧运动对2型糖尿病周围神经病变患者感觉阈值、神经传导速度和血液流变学的影响 |
| Effects of Low Frequency Pulse Stimulation Acupoint Therapy Combined with Regular Aerobic Exercise on Sensory Threshold, Nerve Conduction Velocity and Hemorheology in Patients with Type 2 Diabetes Peripheral Neuropathy |
| Received:July 06, 2022 Revised:July 31, 2022 |
| DOI：10.13241/j.cnki.pmb.2023.04.031 |
| 中文关键词: 低频脉冲刺激穴位疗法 有氧运动 糖尿病周围神经病变 感觉阈值 神经传导速度 血液流变学 |
| 英文关键词: Low frequency pulse stimulation acupoint therapy Aerobic exercise Diabetes peripheral neuropathy Sensory threshold Nerve conduction velocity Hemorheology |
| 基金项目:贵州省教育厅自然科学基金重大群体创新课题基金项目（黔教合KY字[2017]042） |
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| 中文摘要: |
| 摘要 目的：探讨低频脉冲刺激穴位疗法联合规律有氧运动对2型糖尿病周围神经病变（DPN）患者感觉阈值、神经传导速度和血液流变学的影响。方法：选取2020年1月~2022年1月期间贵州中医药大学第二附属医院收治的DPN患者136例。根据随机数字表法分为对照组（n=68，常规治疗联合规律有氧运动）和研究组（n=68，对照组基础上接受低频脉冲刺激穴位疗法），两组以14 d为1个疗程，均治疗2个疗程。对比两组疗效、感觉阈值、神经传导速度和血液流变学变化。结果：研究组的临床总有效率91.18%（62/68）高于对照组75%（51/68）（P<0.05）。两组治疗2个疗程后腓总神经感觉神经传导速度（SCV）、胫神经SCV、腓总神经运动神经传导速度（MCV）、胫神经MCV均升高，且研究组的变化程度大于对照组（P<0.05）。两组治疗2个疗程后全血黏度值(高切、低切)、红细胞压积、血浆黏度、血小板黏附率均下降，且研究组的变化程度大于对照组（P<0.05）。两组治疗2个疗程后神经症状积分、神经反射、感觉功能和总分均下降，且研究组的变化程度大于对照组（P<0.05）。结论：低频脉冲刺激穴位疗法联合规律有氧运动治疗DPN患者，可提高神经传导速度，改善感觉阈值和血液流变学。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effects of low frequency pulse stimulation acupoint therapy combined with regular aerobic exercise on sensory threshold, nerve conduction velocity and hemorheology in patients with type 2 diabetes peripheral neuropathy (DPN). Methods: 136 patients with DPN who were admitted to The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine from January 2020 to January 2022 were selected. According to random number table method, they were divided into control group (n=68, conventional treatment combined with regular aerobic exercise) and study group (n=68, received low frequency pulse stimulation acupoint therapy on the basis of control group). Both groups were treated for 14 days as a course of treatment, and both groups were treated for 2 courses. Efficacy, sensory threshold, nerve conduction velocity and hemorheology changes were compared between the two groups. Results: The total effective rate of the study group was 91.18% (62/68), which was higher than 75% (51/68) of the control group (P<0.05). The nervus peroneus communis conduction velocity (SCV), tibial nerve conduction velocity (SCV), nervus peroneus communis conduction velocity (MCV) and tibial nerve conduction velocity (MCV) were all increased in both groups 2 courses after treatment, and the degree of change of the study group was greater than that of the control group (P<0.05). 2 courses after treatment, whole blood viscosity (high shear, low shear), hematocrit, plasma viscosity and platelet adhesion rate decreased in both groups, and the degree of change of the study group was greater than that of the control group (P<0.05). Neurological symptom score, neurological reflex, sensory function and total score decreased in both groups 2 courses after treatment, and the degree of change of the study group was greater than that of the control group (P<0.05). Conclusion: Low frequency pulse stimulation combined with regular aerobic exercise can improve nerve conduction velocity, sensory threshold and hemorheology in patients with DPN. |
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