| 王晓辉,许婷娜,刘 霞,李灵格,刘 欣.双针刺疗法在孕足月初产妇催产中的应用效果及对应激反应和内源性神经递质的影响[J].现代生物医学进展英文版,2023,(3):575-578. |
| 双针刺疗法在孕足月初产妇催产中的应用效果及对应激反应和内源性神经递质的影响 |
| Application Effect of Double Acupuncture Therapy on Oxytocin in Full-Term Primiparas and its Influence on Stress Response and Endogenous Neurotransmitters |
| Received:April 26, 2022 Revised:May 21, 2022 |
| DOI：10.13241/j.cnki.pmb.2023.03.035 |
| 中文关键词: 双针刺疗法 足月初产妇 催产 疗效 应激反应 内源性神经递质 |
| 英文关键词: Double acupuncture therapy Full-term primiparas Oxytocin Efficacy Stress response Endogenous neurotransmitters |
| 基金项目:河北省中医药管理局科研计划项目（2020007） |
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| 中文摘要: |
| 摘要 目的：研究双针刺疗法在孕足月初产妇催产中的应用效果及对应激反应和内源性神经递质的影响。方法：选取2020年3月~2022年5月期间我院妇产科收治的孕足月初产妇102例。根据随机数字表法分为对照组（51例）和研究组（51例）。产妇在临产宫口开至3 cm（T0）后，对照组不予以任何镇痛方法干预，研究组给予双针刺疗法干预。比较两组催产疗效、产程情况、宫颈成熟指标、应激反应和疼痛、内源性神经递质指标的变化情况。结果：研究组的临床总有效率高于对照组（P<0.05）。研究组的总产程、第一产程、第二产程、第三产程时间均短于对照组（P<0.05）。研究组的宫颈口扩张、宫颈管消退、先露位置、宫颈硬度、宫口位置大于对照组（P<0.05）。两组宫颈口开10 cm（T1）的血糖、皮质醇水平升高，但研究组低于对照组（P<0.05）。两组T1的视觉疼痛模拟（VAS）评分、P物质（SP）、β-内啡肽（β-EP）、神经肽Y（NPY）升高，但研究组低于对照组（P<0.05）。结论：孕足月初产妇采用双针刺疗法可提高催产疗效，促进宫颈成熟，缩短产程时间，同时还可减少内源性神经递质的释放，减轻产妇应激反应。 |
| 英文摘要: |
| ABSTRACT Objective: To study the application effect of double acupuncture therapy on oxytocin and its influence on stress response and endogenous neurotransmitters in full-term primiparas. Methods: 102 full-term primiparas who were admitted to the Department of Obstetrics and Gynecology of our hospital from March 2020 to May 2022 were selected. According to the random number table method, they were divided into control group (51 cases) and study group (51 cases). When the uterine orifice was opened to 3cm (T0), the control group was no intervention with any analgesic method, while the study group was given double acupuncture therapy intervention. The efficacy of oxytocin, labor stage, cervical maturation indicators, stress response and pain, and endogenous neurotransmitter indicators changes were compared in the two groups. Results: The total effective rate in the study group was higher than that in the control group(P<0.05). The total stage of labor, the first stage of labor, the second stage of labor, and the third stage of labor in the study group were shorter than those in the control group(P<0.05). The dilatation of cervical orifice, regression of cervical canal, first exposed position, cervical hardness and uterine orifice position in the study group were significantly higher than those in the control group (P<0.05). The levels of blood glucose and cortisol in the two groups at 10 cm(T1) cervical opening were increased, but the study group was lower than the control group (P<0.05). The visual pain analogue scale (VAS) score, substance P (SP), β-endorphin (β-EP) and neuropeptide Y (NPY) in the two groups at T1 were increased, but the study group was lower than the control group(P<0.05). Conclusion: Double acupuncture therapy for full-term primiparas can improve the effect of oxytocin, promote cervical maturation, shorten the time of labor, reduce the release of endogenous neurotransmitters, and reduce the stress response of primipara. |
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