| 甘 静,王 帅,翟 琪,高 华,李 颖.NLR、MPVLR、MPV在全膝关节置换术后急性下肢深静脉血栓形成诊断中的影响价值[J].现代生物医学进展英文版,2022,(18):3596-3600. |
| NLR、MPVLR、MPV在全膝关节置换术后急性下肢深静脉血栓形成诊断中的影响价值 |
| Influence Value of NLR, MPVLR and MPV in the Diagnosis of Acute Lower Extremity Deep Vein Thrombosis after Total Knee Arthroplasty |
| Received:March 27, 2022 Revised:April 23, 2022 |
| DOI：10.13241/j.cnki.pmb.2022.18.038 |
| 中文关键词: NLR MPVLR MPV 全膝关节置换术 急性下肢深静脉血栓 诊断 |
| 英文关键词: NLR MPVLR MPV Total knee arthroplasty Acute lower extremity deep vein thrombosis Diagnosis |
| 基金项目:河北省卫生健康委医学科学研究计划项目（J2021RD2118） |
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| 中文摘要: |
| 摘要 目的：分析全膝关节置换术后急性下肢深静脉血栓（DVT）形成中NLR、MPVLR、MPV的临床诊断价值。方法：于本院2020年10月-2021年10月接受全膝关节置换术患者中筛选80例开展研究，纳入对象接受手术治疗后3到5日内接受彩色超声下肢DVT检查，依据检查证实是否发生下肢DVT作为分组标准，将结果证实发生下肢DVT患者43例纳入观察组，未发生的37例纳入对照组。两组同时接受血常规检查，汇总平均血小板体积（MPV）、淋巴细胞计数、中性粒细胞，并依据结果计算中性粒细胞/淋巴细胞计数（NLR），平均血小板体积/淋巴细胞计数（MPVLR），对患者临床资料展开回顾性分析，判断发生/未发生组别患者各项指标从差异，进而评价MPV、NLR、MPVLR对术后急性下肢DVT形成诊断的诊断价值。结果：发生下肢DVT与未发生下肢DVT患者，在性别、年龄、慢性病史（高血压、糖尿病）、吸烟史、体质量指数等方面，未见明显差异（P>0.05）。和未发生下肢DVT患者相比，发生下肢DVT患者中心粒细胞相对较低，淋巴细胞和血小板计数相对加高（P<0.05）。两组在白细胞上差异不大（P>0.05）。发生下肢DVT患者MPV、NLR、MPVLR明显高于未发生手术患者（P<0.05）；肿胀天数在7天及以上、高于7天患者在NLR指标上差异不大（P＞0.05），而在MPVLR上组间有统计学差异（P<0.05）。结论：MPV、NLR、MPVLR指标对于判断全膝关节置换术治疗后判断是否发生急性下肢DVT具有较高诊断价值，其中MPVLR可作为下肢DVT早期诊断典型指标，为临床提供疾病判断依据，值得重视。 |
| 英文摘要: |
| ABSTRACT Objective: To analyze the clinical diagnostic value of NLR, MPVLR and MPV in acute lower extremity deep vein thrombosis (DVT) formation after total knee arthroplasty. Methods: A total of 80 patients who underwent total knee arthroplasty in our hospital from October 2020 to October 2021 were screened for research, and the included subjects underwent color ultrasound lower extremity DVT examination within 3 to 5 days after the surgery. DVT was used as the grouping standard, 43 patients with DVT of lower extremities confirmed by the results were included in the observation group, and 37 patients who did not occur were included in the control group. The two groups received routine blood tests at the same time, and the mean platelet volume (MPV), lymphocyte count, and neutrophil count were summarized, and the neutrophil/lymphocyte count (NLR) and mean platelet volume/lymphocyte count (MPVLR) were calculated according to the results), retrospectively analyzed the clinical data of the patients, and judged the differences of various indicators between the patients with and without occurrence, and then evaluated the diagnostic value of MPV, NLR, and MPVLR in the diagnosis of postoperative acute lower extremity DVT. Results: There was no significant difference in gender, age, history of chronic diseases (hypertension, diabetes), smoking history, and body mass index between patients with DVT and those without DVT (P>0.05). Compared with patients without lower extremity DVT, patients with lower extremity DVT had relatively lower neutrophils and higher lymphocyte and platelet counts(P<0.05). There was no significant difference in white blood cells between the two groups (P>0.05). MPV, NLR and MPVLR in patients with lower extremity DVT were significantly higher than those in patients without surgery(P<0.05); patients with swelling days of 7 days or more and more than 7 days had little difference in NLR indexes(P>0.05). There was a statistical difference between groups on MPVLR(P<0.05). Conclusion: MPV, NLR and MPVLR indexes have high diagnostic value for judging whether acute lower extremity DVT occurs after total knee arthroplasty. MPVLR can be used as a typical index for early diagnosis of lower extremity DVT, and provides a basis for clinical diagnosis of the disease, which deserves attention. |
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