| 鹿振辉,刘 娜,石 颖,赵海颖,董 艳.肠内营养不同递增输注速度对重症急性胰腺炎患者喂养耐受性、生存质量和胃肠功能恢复的影响[J].现代生物医学进展英文版,2022,(10):1846-1850. |
| 肠内营养不同递增输注速度对重症急性胰腺炎患者喂养耐受性、生存质量和胃肠功能恢复的影响 |
| Effects of Different Incremental Infusion Speed of Enteral Nutrition on Feeding Tolerance, Quality of Life and Gastrointestinal Function Recovery in Patients with Severe Acute Pancreatitis |
| Received:November 08, 2021 Revised:November 30, 2021 |
| DOI：10.13241/j.cnki.pmb.2022.10.010 |
| 中文关键词: 肠内营养 输注速度 重症急性胰腺炎 喂养耐受性 生存质量 胃肠功能 |
| 英文关键词: Enteral nutrition Infusion speed Severe acute pancreatitis Feeding tolerance Quality of life Gastrointestinal function |
| 基金项目:北京市医院管理局"青苗"计划项目（QML20180206） |
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| 中文摘要: |
| 摘要 目的：观察肠内营养不同递增输注速度对重症急性胰腺炎（SAP）患者喂养耐受性、生存质量和胃肠功能恢复的影响。方法：选取2019年3月~2021年2月期间我院收治的SAP患者120例，按照随机数字表法分为低速组、中速组和高速组，各为40例，输注速度递增幅度由低到高给予肠内营养。对比三组患者的腹内压、喂养耐受性、生存质量和胃肠功能恢复情况。结果：干预8 h后、干预16 h后、干预20 h后低速组腹内压低于高速组、中速组，而中速组低于高速组（P<0.05）。低速组排气排便恢复时间、肠鸣音恢复时间、经口进食时间、腹胀缓解时间短于中速组、高速组，中速组则短于高速组（P<0.05）。低速组干预7 d后世界卫生组织生存质量简明量表（WHO-QOL-BREF）各维度评分高于中速组、高速组，中速组则高于高速组（P<0.05）。低速组喂养不耐受发生率低于中速组、高速组，中速组则低于高速组（P<0.05）。结论：肠内营养低速递增输注有利于防止腹内压升高，提高SAP患者喂养耐受性，促进胃肠功能恢复，进而提高患者生存质量。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effects of different incremental infusion speed of enteral nutrition on feeding tolerance, quality of life and gastrointestinal function recovery in patients with severe acute pancreatitis (SAP). Methods: 120 patients with SAP who were treated in our hospital from March 2019 to February 2021 were selected, and they were randomly divided into low-speed group, medium-speed group and high-speed group, with 40 cases in each group, the increasing range of infusion rate was from low to high, and enteral nutrition was given. The intra-abdominal pressure, feeding tolerance, quality of life and gastrointestinal function recovery of the three groups were compared. Results: 8 h after intervention, 16 h after intervention and 20 h after intervention, the intra-abdominal pressure in low-speed group was lower than that in high-speed group and medium-speed group, while that in medium-speed group was lower than that in high-speed group (P<0.05). The exhaust and defecation recovery time, bowel sound recovery time, oral feeding time and abdominal distension relief time in low-speed group were shorter than those in medium-speed group and high-speed group, while those in medium-speed group were shorter than those in high-speed group (P<0.05). 7 d after intervention, the scores of all dimensions of the world health organization the quality of life-BREF (WHO-QOL-BREF) in the low-speed group were higher than those in the medium-speed group and the high-speed group, while those in the medium-speed group were higher than those in the high-speed group (P<0.05). The incidence of feeding intolerance in low-speed group was lower than that in medium-speed group and high-speed group, and that in medium-speed group was lower than that in high-speed group(P<0.05). Conclusion: The low-speed incremental infusion of enteral nutrition is helpful to prevent the increase of intra-abdominal pressure, improve the feeding tolerance of patients with SAP, promote the gastrointestinal function recovery, and then improve the quality of life of patients. |
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