| 柳月仙,陈艳华,柴 娜,韩保学,陈艳丽.成人急性淋巴细胞白血病患者复发恐惧的影响因素及与社会支持的相关性研究[J].现代生物医学进展英文版,2022,(8):1552-1556. |
| 成人急性淋巴细胞白血病患者复发恐惧的影响因素及与社会支持的相关性研究 |
| Influence Factors of Relapse Fear and its Correlation with Social Support in Adult Acute Lymphoblastic Leukemia Patients |
| Received:September 23, 2021 Revised:October 17, 2021 |
| DOI：10.13241/j.cnki.pmb.2022.08.032 |
| 中文关键词: 急性淋巴细胞白血病 复发恐惧 社会支持 影响因素 |
| 英文关键词: Acute lymphoblastic leukemia Relapse fear Social support Influencing factor |
| 基金项目:山东省重点研发计划项目（2016GSF201019） |
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| 中文摘要: |
| 摘要 目的：探讨影响成人急性淋巴细胞白血病（ALL）患者复发恐惧的因素，分析复发恐惧与社会支持的相关性。方法：选择2017年5月至2021年5月我院收治的80例成人ALL患者，采用疾病进展恐惧简化量表（FoP-Q-SF）和社会支持评定量表（SSRS）对其进行评估，以单因素及多因素Logistic回归分析成人ALL患者复发恐惧的影响因素，采用Pearson相关分析成人ALL患者复发恐惧与社会支持的关系。结果：80例成人ALL患者的FoP-Q-SF评分为31～50分，平均（39.02±7.91）分，其中FoP-Q-SF评分≥34分者49例（高复发恐惧组），占比达61.25%，FoP-Q-SF评分＜34分者31例（低复发恐惧组）。单因素分析结果显示：高复发恐惧组与低复发恐惧组在年龄、性别、个人月收入、是否有医疗保险以及社会支持方面比较差异具有统计学意义（P＜0.05）。进一步多因素Logistic回归分析结果显示：年龄18～45岁、女性、个人月收入≤3000元、社会支持较少是成人ALL患者复发恐惧的危险因素（P＜0.05）。高复发恐惧组SSRS各维度（主观支持、客观支持、对支持利用度）评分及总分均低于低复发恐惧组（P＜0.05）。Pearson相关性分析结果显示：成人ALL患者FoP-Q-SF评分与SSRS评分呈负相关（P＜0.05）。结论：成人ALL患者普遍存在复发恐惧心理，年龄、性别、个人月收入和社会支持是其影响因素，且社会支持水平与复发恐惧程度呈负相关。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the factors affecting relapse fear in adult acute lymphoblastic leukemia (ALL) patients, and to analyze the correlation between relapse fear and social support. Methods: 80 adult ALL patients who were treated in our hospital from May 2017 to May 2021 were selected, the disease Fear of Progression Questionnaire-Short Form (FoP-Q-SF) and social support rating scale (SSRS) were used for their questionnaire survey. Multivariate Logistic regression was used to analyze the influencing factors of relapse fear in adult ALL patients, and Pearson correlation was used to analyze the relationship between relapse fear and social support in adult ALL patients. Results: The FoP-Q-SF scores of 80 adult ALL patients ranged from 31 to 50, with an average of (39.02±7.91) scores. Among them, 49 patients with FoP-Q-SF score ≥34 scores (high relapse fear group), accounting for 61.25%, and 31 patients with FoP-Q-SF score < 34 (low relapse fear group). Univariate analysis showed that there were significant differences in age, gender, personal monthly income, medical insurance and social support between high relapse fear group and low relapse fear group(P＜0.05). Further multivariate Logistic regression analysis showed that age 18~45 years old, female, personal monthly income ≤3000 yuan and less social support were the risk factors of relapse fear in adult ALL patients(P＜0.05). The scores and total scores of SSRS in each dimension (subjective support, objective support and utilization of support) in the high relapse fear group were lower than those in the low relapse fear group(P＜0.05). Pearson correlation analysis showed that there was a significant negative correlation between FoP-Q-SF score and SSRS score in adult ALL patients(P＜0.05). Conclusion: Adult ALL patients generally have relapse fear. Age, gender, economic income level and social support are their influencing factors. The level of social support is negatively correlated with the degree of relapse fear. |
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