| 曹 羽,龚航军,韩 刚,张 云,张言言,张 旭,胡 建.吲哚菁绿荧光显像技术在腹腔镜结直肠癌根治术中的临床应用价值分析[J].现代生物医学进展英文版,2022,(8):1475-1479. |
| 吲哚菁绿荧光显像技术在腹腔镜结直肠癌根治术中的临床应用价值分析 |
| Clinical Application Value Analysis of Indocyanine Green Fluorescence Imaging Technology in Laparoscopic Radical Resection of Colorectal Cancer |
| Received:September 03, 2021 Revised:September 27, 2021 |
| DOI：10.13241/j.cnki.pmb.2022.08.015 |
| 中文关键词: 吲哚菁绿荧光显像技术 腹腔镜结直肠癌根治术 吻合口漏 吻合口出血 并发症 |
| 英文关键词: Indocyanine green fluorescence imaging technology Laparoscopic radical resection of colorectal cancer Anastomotic leakage Anastomotic bleeding Complications |
| 基金项目:上海市卫计委中医药科研基金项目(2018LQ018) |
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| 中文摘要: |
| 摘要 目的：探讨吲哚菁绿荧光显像技术在腹腔镜结直肠癌根治术中的临床应用价值。方法：选取2020 年6月到2021年6月于我院行腹腔镜结直肠癌根治术的患者112例，按照随机数字表法分为研究组和对照组，每组各56例。两组均采用腹腔镜结直肠癌根治术治疗，研究组术中应用吲哚菁绿荧光显像技术观察吻合口肠段血运情况。比较两组患者手术相关指标、术后并发症发生率、吻合口漏、吻合口出血发生率及围手术期死亡率。结果：两组患者术中均无死亡，两组患者术中出血量、手术时间、首次肛门排气时间、下床活动时间及术中死亡率比较无统计学差异（P>0.05）。研究组腹腔出血、腹腔感染、吻合口漏、吻合口出血发生率显著低于对照组（P<0.05），两组肠梗阻、切口感染、围手术期死亡率比较无统计学差异（P>0.05）。结论：应用吲哚菁绿荧光显像技术可以显著降低腹腔镜结直肠癌根治术患者腹腔出血、腹腔感染、吻合口漏、吻合口出血发生率，在腹腔镜结直肠癌根治术中具有较好的应用价值。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical application value of indocyanine green fluorescence imaging technology in laparoscopic radical resection of colorectal cancer. Methods: 112 patients with colorectal cancer who underwent laparoscopic radical resection of colorectal cancer in our hospital from June 2020 to June 2021 were selected, and they were randomly divided into study group and control group by the digital random method, 56 cases in each group. Both groups were treated with laparoscopic radical resection of colorectal cancer. Indocyanine green fluorescence imaging technology was used to observe the blood supply of anastomotic intestinal segment in the study group. The intraoperative conditions, postoperative complications, anastomotic leakage, incidence of anastomotic bleeding and perioperative mortality were compared between the two groups. Results: There was no intraoperative death between the two groups. There were no significant differences in intraoperative bleeding, operation time, exhaust time, out of bed activity time and intraoperative mortality between the two groups(P>0.05). The incidence of abdominal bleeding, abdominal infection, anastomotic leakage and anastomotic bleeding in the study group were significantly lower than those in the control group(P<0.05). There were no significant differences in intestinal obstruction, incision infection and perioperative mortality between the two groups(P>0.05). Conclusion: The application of indolyanine green fluorescence imaging technology can significantly reduce the incidence of anastomotic leakage and anastomotic bleeding in laparoscopic radical resection of colorectal cancer, which has good application value in laparoscopic radical resection of colorectal cancer. |
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