| 杨 旭,洪 毅,黄 莹,吕 妍,王及氓.胚胎移植术前指导患者憋尿对移植结局影响的研究[J].现代生物医学进展英文版,2022,(8):1466-1469. |
| 胚胎移植术前指导患者憋尿对移植结局影响的研究 |
| Study on the Effect of Guiding Patients to Hold Back Urine before Embryo Transfer on the Outcome of Embryo Transfer |
| Received:October 23, 2021 Revised:November 18, 2021 |
| DOI：10.13241/j.cnki.pmb.2022.08.013 |
| 中文关键词: 胚胎移植 憋尿 移植结局 |
| 英文关键词: Embryo transfer Hold back urine Transplant outcome |
| 基金项目:上海市自然科学基金项目（17ZR14054120） |
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| 中文摘要: |
| 摘要 目的：探讨胚胎移植术前患者憋尿准备的细化指导方法，并分析其对患者移植结局的影响。方法：选取2019年9月至2020年12月期间我院收治的194例胚胎移植患者（包括新鲜周期胚胎移植和冻融周期胚胎移植），按随机数字表法分为指导组（101例）和对照组（93例）。对照组患者给予常规指导憋尿，指导组患者在对照组的基础上给予更细化的憋尿指导方法。比较两组总妊娠率、不同年龄段患者的移植妊娠率，分析提前指导憋尿对瘢痕子宫和无子宫手术史患者移植妊娠率的影响。结果：指导组总妊娠率为59.41%，对照组总妊娠率为53.76%，指导组总妊娠率高于对照组，但是未见显著性差异（P>0.05）；在<35岁的患者中，指导组妊娠率（76.47%）高于对照组（58.33%），差异有统计学意义（P<0.05）；在瘢痕子宫和无子宫手术史的患者中，两组移植妊娠率比较未见显著性差异（P>0.05）。结论：胚胎移植术前给予患者细化的憋尿指导方法能提高<35岁患者的移植妊娠率，对瘢痕子宫和无子宫手术史患者的移植妊娠率无明显影响。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the detailed guidance method of hold back urine preparation before embryo transfer, and to analyze the impact on the outcome of embryo transfer. Methods: 194 patients with embryo transfer (including fresh cycle embryo transfer and freeze-thaw cycle embryo transfer) who were treated in our hospital from September 2019 to December 2020 were selected, they were divided into guidance group (101 cases) and control group (93 cases) according to the random number table method. The patients in the control group were given routine guidance to hold back urine, and the patients in the guidance group was given more detailed guidance methods to hold back urine on the basis of the control group. The total pregnancy rate, transplant pregnancy rate of patients of different ages were compared between the two groups. The effect of early guidance to hold urine on the pregnancy rate of transplantation in patients with scar uterus and patients without uterine surgery history was analyzed. Results: The total pregnancy rate was 59.41% in the guidance group, and 53.76% in the control group. The total pregnancy rate in the guidance group was higher than that in the control group, but there was no significant difference (P>0.05). In patients < 35 years old, the pregnancy rate in the guidance group (76.47%) was higher than that in the control group (58.33%), the difference was statistically significant (P<0.05). In patients with scar uterus and without uterine surgery history, there was no significant difference in the transplantation pregnancy rate between the two groups (P>0.05). Conclusion: Detailed urine holding guidance before embryo transfer can improve the transplantation pregnancy rate of patients <35 years old, but has no significant effect on the transplantation pregnancy rate of patients with scar uterus and without uterine surgery history. |
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