| 张海萍,代乐芳,盘文健,李凤明,秦文婷,杨少丽,姚 臻.不同时间段睡眠剥夺配合改良式水合氯醛保留灌肠法在婴幼儿肺功能检查中的效果分析[J].现代生物医学进展英文版,2022,(3):544-547. |
| 不同时间段睡眠剥夺配合改良式水合氯醛保留灌肠法在婴幼儿肺功能检查中的效果分析 |
| Analysis of the Effect of Sleep Deprivation Combined with Modified Chloral Hydrate Retention Enema in Infants and Young Children's Pulmonary Function Examination |
| Received:May 26, 2021 Revised:June 22, 2021 |
| DOI：10.13241/j.cnki.pmb.2022.03.030 |
| 中文关键词: 睡眠剥夺 水合氯醛 婴幼儿 肺功能检查 镇静效果 不良反应 |
| 英文关键词: Sleep deprivation Chloral hydrate Infants and young children Pulmonary function examination Sedative effect Adverse reactions |
| 基金项目:广西壮族自治区卫生健康委员会科技计划项目（Z20180568） |
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| 中文摘要: |
| 摘要 目的：探讨不同时间段睡眠剥夺配合改良式水合氯醛保留灌肠法在婴幼儿肺功能检查中的镇静效果。方法：前瞻性选取2018年2月~2020年8月本院收治并需行肺功能检查的婴幼儿临床资料，纳入194例婴幼儿作为研究对象，根据随机数字表法简单随机分为四组。对照组（n=48）不进行睡眠剥夺，短时段组（n=48）行短时段睡眠剥夺，中时段组（n=49）行中时段睡眠剥夺，长时段组（n=49）行长时段睡眠剥夺。对比四组婴幼儿的入睡时间、镇静效果及不良反应。结果：四组婴幼儿入睡时间的组间差异具有统计学意义（P＜0.05）。与对照组相比，联合睡眠剥夺干预的三组婴幼儿在10 min内进入睡眠的例数明显增多；随着睡眠剥夺时间增加，睡眠剥夺的三组婴幼儿超过30 min才进入睡眠的例数明显少于对照组。四组婴幼儿镇静效果的组间比较差异具有统计学意义（P＜0.05）；与对照组相比，联合睡眠剥夺干预的三组婴幼儿镇静效果明显升高，镇静总有效率均高于对照组（P＜0.05）。在实验期间，四组婴幼儿均出现不同类型的不良反应，各类型不良反应发生率及总发生率的组间比较，差异均无统计学意义（P>0.05），但长时段组出现情绪烦躁的比例略高。结论：睡眠剥夺配合改良式水合氯醛灌肠法对婴幼儿具有良好的镇静效果，但长时段睡眠剥夺可能会使其情绪烦躁，需在检查完成后悉心安抚婴幼儿情绪。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the sedative effect of sleep deprivation combined with modified chloral hydrate retention enema in infants and young children's pulmonary function examination. Methods: Prospectively selected the clinical data of infants and young children who were admitted to our hospital from February 2018 to August 2020 and required pulmonary function tests. 194 infants and young children were included as the research objects, and they were simply randomly divided into 4 groups according to the random number table method. The control group (n=48) did not undergo sleep deprivation, the short-term group(n=48) was short-term sleep deprivation, the middle-term group (n=49) the middle-term sleep deprivation, the long-term group(n=49) was the leader period sleep deprivation. The time to fall asleep, sedative effects and adverse reactions of the 4 groups of infants and young children were compared. Results: The difference in time to fall asleep between the four groups of infants and young children was statistically significant (P<0.05).Compared with the control group, the number of infants and young children in the three groups of combined sleep deprivation intervention that went to sleep within 10 minutes was significantly increased; with the increase in sleep deprivation, the number of infants and young children in the three groups of sleep deprivation that went to sleep after 30 minutes was significantly less than the control group.The difference in the sedative effect of the four groups of infants and young children was statistically significant (P<0.05); compared with the control group, the three groups of infants and young children combined with sleep deprivation intervention had a significantly higher sedative effect, and the total effective rate of sedation was higher than that of the control group(P<0.05). During the experiment, the four groups of infants and young children had different types of adverse reactions, and there was no statistically significant difference in the incidence and total incidence of each type of adverse reaction among the groups (P>0.05), but the the proportion of emotional irritability in the long-term group was slightly higher. Conclusion: Sleep deprivation combined with the modified chloral hydrate retention enema has a good sedative effect on infants and young children, but long-term sleep deprivation may make them emotionally irritable, so they need to be carefully calmed after the examination. |
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