| 王生兰,王榀华,李 洁,海妤婷,吴 婷.产后逐瘀胶囊联合米非司酮治疗产后恶露不尽的临床疗效观察[J].现代生物医学进展英文版,2021,(24):4791-4794. |
| 产后逐瘀胶囊联合米非司酮治疗产后恶露不尽的临床疗效观察 |
| Clinical Observation of Postpartum Zhuyu Capsule Combined with Mifepristone in the Treatment of Postpartum Lochia |
| Received:May 20, 2021 Revised:June 16, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.24.040 |
| 中文关键词: 产后逐瘀胶囊 米非司酮 产后恶露不尽 疗效 |
| 英文关键词: Postpartum Zhuyu capsule Mifepristone Postpartum lochia endless Curative effect |
| 基金项目:青海省卫生健康委基金项目（2019-wjzdx-71） |
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| 中文摘要: |
| 摘要 目的：探讨产后逐瘀胶囊联合米非司酮对产后恶露不尽的治疗效果。方法：选取2018年6月~2020年12月期间青海红十字医院接受诊治的128例产后恶露不尽患者，根据随机数字表法分为对照组和观察组各64例。对照组给予米非司酮治疗，在对照组的基础上观察组另加服产后逐瘀胶囊治疗，对比两组疗效、子宫三径、凝血功能指标、平均恶露干净时间、恶露量以及不良反应情况。结果：观察组的总有效率高于对照组（P<0.05）。两组治疗2周后的子宫三径比治疗前缩小，且观察组较对照组更小（P<0.05）。两组治疗2周后纤维蛋白原（FIB）、凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、凝血酶时间（TT）均下降，且观察组低于对照组（P<0.05）。观察组的恶露量少于对照组，平均恶露干净时间短于对照组（P<0.05）。两组不良反应对比无明显差异（P>0.05）。结论：产后逐瘀胶囊联合米非司酮治疗产后恶露不尽疗效可靠，能够有效阻止恶露，促进子宫复旧，改善机体凝血功能，且安全性较好。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the therapeutic effect of postpartum Zhuyu Capsule Combined with mifepristone on postpartum lochia. Methods: 128 cases of postpartum lochia in Qinghai Red Cross Hospital from June 2018 to December 2020 were selected, according to the random number table method, they were divided into control group and observation group with 64 cases in each group. The control group was treated with mifepristone, and the the observation group was additionally treated with postpartum Zhuyu Capsule on the basis of the control group. The curative effect, uterine three diameter, coagulation function index, average lochia cleaning time, lochia volume and adverse reactions between the two groups were compared. Results: The total effective rate of observation group was higher than that of control group(P<0.05). 2 weeks after treatment, the uterine three diameter in the two groups was smaller than that before treatment, and the observation group was smaller than the control group(P<0.05). There was no difference in adverse reactions between the two groups(P>0.05). 2 weeks after treatment, fibrinogen (FIB), prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) in the two groups decreased, and the observation group was lower than the control group (P<0.05). The lochia volume in the observation group was less than that in the control group, and the average lochia cleaning time in the observation group was shorter than those in the control group(P<0.05). There was no significant difference in adverse reactions between the two groups (P>0.05). Conclusion: The combination of postpartum Zhuyu Capsule and mifepristone has reliable curative effect, can effectively prevent the Lulu, promote the uterine recovery, improve the coagulation function of the body, and has good safety. |
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