| 池原颖,郑广瑛,陈 涛,程安然,陈 果.不同类型弱视儿童视网膜神经纤维层与预后视力恢复的相关性[J].现代生物医学进展英文版,2021,(24):4729-4732. |
| 不同类型弱视儿童视网膜神经纤维层与预后视力恢复的相关性 |
| The Correlation between Retinal Nerve Fiber Layer and Prognosis of Visual Acuity Recovery in Children with Different Types of Amblyopia |
| Received:April 28, 2021 Revised:May 23, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.24.026 |
| 中文关键词: 弱视 视网膜神经纤维层 视力恢复 相关性 光学相干断层成像 |
| 英文关键词: Amblyopia Retina Retinal nerve fiber layer Correlation Optical coherence tomography |
| 基金项目:河南省基础研究计划项目(142300413203) |
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| 中文摘要: |
| 摘要 目的：探讨不同类型弱视儿童视网膜神经纤维层（RNFL）与预后视力恢复的相关性。方法：选择2017年6月至2020年6月在本院眼科就诊的80例弱视患儿作为研究对象，其中屈光参差性弱视32例（A组）、斜视性弱视28例（B组）、屈光不正性弱视20例（C组）。三组患儿都进行常规检查与光学相干断层成像（OCT），调查随访患儿的预后视力恢复情况，并进行相关性分析。结果：三组的视盘面积、盘沿面积、校正视盘面积、校正盘沿面积、等效球镜绝对值、眼轴长度等数据对比无差异（P>0.05）。B组与C组的上方、鼻侧、下方、颞侧、全周的RNFL厚度都高于A组（P<0.05），C组高于B组（P<0.05）。随访截止时间为2021年1月，A组、B组与C组的总有效率分别为87.5 %、85.7 %和85.0 %，对比无差异（P>0.05）。Pearson线性相关分析显示预后总有效率与上方、鼻侧、下方、颞侧、全周的RNFL厚度均存在相关性（P<0.05）。结论：不同类型弱视儿童的视网膜神经纤维层结构厚度存在差异，与患儿的预后视力恢复存在相关性。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the correlation between the retinal nerve fiber layer of children with different types of amblyopia and the prognosis of vision recovery. Methods: From June 2017 to June 2020, 80 cases of children with amblyopia who were treated in our Hospital, ophthalmology department were selected as the research objects, included 32 cases of anisometropic amblyopia (group A), 28 cases of strabismus amblyopia (group B), 20 cases of refractive amblyopia (group C). All the cases were underwent routine examinations and optical coherence tomography (OCT), Were to investigate the prognosis of the followed-up children and given correlation analysis. Results: There were no difference in the absolute value of the equivalent spherical lens, eye axis length, optic disc area, disc edge area, corrected optic disc area, and corrected disc edge area of the three groups (P>0.05). The thickness of RNFL in the upper, nasal, inferior, temporal and whole weeks of group B and C were higher than that of group A(P<0.05), and group C were higher than group B (P<0.05). The deadline for followed-up were January 2021, the total effective rates of group A, group B and group C were 87.5 %, 85.7 %, and 85.0 %, respectively, and there were no difference in comparison (P>0.05). Pearson linear correlation analysis showed that the total effective prognosis were correlated with the thickness of RNFL above, nasal, inferior, temporal, and whole week (P<0.05). Conclusion: There has differences in the thickness of the retinal nerve fiber layer structure in children with different types of amblyopia, which are related to the prognosis of the children's vision recovery. |
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