| 金翻亮,任补元,冰 峰,云 跃,贺彦龙.导管接触性溶栓同期球囊扩张+支架治疗血栓性髂静脉压迫综合征的疗效[J].现代生物医学进展英文版,2021,(24):4709-4712. |
| 导管接触性溶栓同期球囊扩张+支架治疗血栓性髂静脉压迫综合征的疗效 |
| The Effect of Catheter Contact Thrombolysis with Balloon Expansion and Stent in the Treatment of Thrombotic Iliac Vein Compression Syndrome |
| Received:February 06, 2021 Revised:February 28, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.24.022 |
| 中文关键词: 导管接触溶栓 球囊扩张 支架 髂静脉压迫综合征 下肢深静脉血栓 |
| 英文关键词: Catheter contact thrombolysis Balloon expansion Stent Iliac vein compression syndrome Deep vein thrombosis of the lower extremities |
| 基金项目:内蒙自治区自然科学基金重点项目(2016MS0878) |
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| 中文摘要: |
| 摘要 目的：为提高治疗效率，本研究对髂静脉压迫综合征合并下肢深静脉血栓患者的导管接触溶栓同期球囊扩张+支架治疗方案和分期治疗方案进行比较。方法：以65例髂静脉压迫综合征合并下肢深静脉血栓患者为研究对象，根据治疗方法分为研究组和对照组，研究组32例，进行导管接触溶栓同期球囊扩张+支架治疗，对照组33例，进行导管接触溶栓分期球囊扩张+支架治疗。以治疗前后患者大腿围、小腿围、血管通畅评分，手术指标（住院时间、住院次数、溶栓时间及穿刺次数），并发症（血栓复发、出血以及肺栓塞）及深静脉血栓后遗症为指标，考察两组疗效。结果：两组患者大腿围、小腿围和静脉畅通评分在治疗前均无显著差异（P＞0.05），经过治疗，两组大腿围、小腿围和静脉畅通评分均显著改善（P＜0.05），但两组间各项指标无显著差异（P＞0.05）。研究组患者住院时间、住院次数、溶栓时间及穿刺次数均显著低于对照组（P＜0.05）。研究组血栓复发0例，对照组血栓复发4例，有显著差异（P＜0.05）；研究组出血1例，肺栓塞0例，对照组出血2例，肺栓塞0例，两组出血和肺栓塞情况比较，无显著差异（P＞0.05）。研究组PTS发生率为6.25 %，显著低于对照组的18.18 %（P＜0.05）。结论：导管接触溶栓同期球囊扩张+支架治疗方案对髂静脉压迫综合征合并下肢深静脉血栓有良好的疗效。 |
| 英文摘要: |
| ABSTRACT Objective: In order to improve the efficiency of treatment, this study compared catheter contact thrombolysis in patients with iliac vein compression syndrome and deep vein thrombosis at the same time as balloon dilatation + stent treatment plan and staged treatment plan. Methods: Sixty-five patients with iliac vein compression syndrome combined with deep vein thrombosis of the lower extremities were taken as the research objects. According to the treatment method, they were divided into study group and control group. Thirty-two patients in the study group received catheter-contact thrombolysis and balloon dilatation + stent therapy at the same time; 33 patients in the control group received catheter-contact thrombolysis and balloon dilatation+ stent therapy. The patient's thigh circumference, calf circumference, vascular patency score, surgical indicators (hospitalization time, hospitalization times, thrombolysis time and puncture times), complications (thrombosis recurrence, bleeding, and pulmonary embolism) and sequelae of deep vein thrombosis are used as indicators. Results: The thigh circumference, calf circumference and venous patency scores of the two groups of patients were not significantly different before treatment(P>0.05). After treatment, the thigh circumference, calf circumference and venous patency scores of the two groups were significantly improved (P<0.05). There was no significant difference in various indicators between the two (P>0.05). The length of hospitalization, the number of hospitalizations, the time of thrombolysis and the number of punctures in the study group were significantly lower than those in the control group(P<0.05). There were 0 cases of thrombosis recurrence in the study group and 4 cases of thrombosis recurrence in the control group (P＜0.05). There were 1 bleeding in the study group, 0 pulmonary embolism, 2 bleeding in the control group, and 0 pulmonary embolism. There was no significant difference in bleeding and pulmonary embolism between the two groups(P>0.05). The incidence of PTS in the study group was 6.25 %, which was significantly lower than 18.18 % in the control group(P<0.05). Conclusion: Catheter contact thrombolysis at the same time balloon dilatation + stent treatment program has a good effect on iliac vein compression syndrome with deep vein thrombosis of lower limbs. |
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