| 陈 媛,张汝秋,陈艳萍,洪彩燕,金凤敏,李斌斌.胃癌患者营养风险与生活质量及近期预后的关系研究[J].现代生物医学进展英文版,2021,(22):4283-4287. |
| 胃癌患者营养风险与生活质量及近期预后的关系研究 |
| Study on the Relationship between Nutritional Risk, Quality of Life and Short-term Prognosis in Patients with Gastric Cancer |
| Received:April 05, 2021 Revised:April 28, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.22.017 |
| 中文关键词: 胃癌 营养风险 影响因素 生活质量 预后 |
| 英文关键词: Gastric cancer Nutritional risk Influencing factors Quality of Life Prognosis |
| 基金项目:福建省自然科学基金项目（2017J01321） |
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| 中文摘要: |
| 摘要 目的：探讨胃癌患者的营养风险的危险因素，并分析其与患者生活质量及近期预后的关系。方法：纳入我院2017年4月～2019年10月收治的胃癌患者81例，利用营养风险筛查2002（NRS2002）评分分析患者有无营养风险，经Logistic多元回归分析胃癌患者营养风险的危险因素。经简明生活质量量表（SF-36）评估患者生活质量并进行比较，前瞻性随访3、12个月，统计患者近期预后，分析胃癌患者NRS2002评分与SF-36评分的相关性。结果：在81例胃癌患者中，营养风险发生率为53.09%。Logistic多元回归分析显示：年龄≥60岁（OR=1.657，95%CI：1.042-2.635）、疼痛分度Ⅲ～Ⅳ度（OR=4.515，95%CI：1.656-12.310）、消化道反应Ⅲ～Ⅳ度（OR=3.947，95%CI：1.599-9.743）是胃癌患者营养风险发生的危险因素（P＜0.05），而营养补充（OR=0.899，95%CI：0.846-0.955）是胃癌患者营养风险发生的保护因素（P＜0.05）。营养风险组情绪角色功能、躯体角色功能、躯体功能、总体健康、心理健康、躯体疼痛评分低于无营养风险组，NRS2002评分高于无营养风险组（P＜0.05）。胃癌患者NRS2002评分与情绪角色功能、躯体角色功能、躯体功能、总体健康、心理健康、躯体疼痛评分呈负相关（P＜0.05）。营养风险组随访3个月的生存率为95.35%，与无营养风险组的100%比较无差异（P＞0.05）。营养风险组随访12个月的生存率为79.07%，低于无营养风险组的94.74%（P＜0.05）。结论：胃癌患者营养风险发生率较高，其发生与多种因素有关，营养风险会影响生活质量和近期预后，临床需及时对胃癌患者进行营养风险评估，并尽早干预。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the risk factors of nutritional risk in patients with gastric cancer, and to analyze the relationship between nutritional risk and patients' quality of life and short-term prognosis. Methods: 81 patients with gastric cancer who were admitted to our hospital from April 2017 to October 2019 were included, and the nutritional risk screening 2002 (NRS2002) score was used to analyze whether the patients had nutritional risk. Logsitc multiple regression analysis was used to analyze the risk factors of nutritional risk in patients with gastric cancer. The quality of life of the patients was assessed and compared by the Concise Quality of Life Scale (SF-36), and the patients were followed up prospectively for 3 and 12 months, and the short-term prognosis of the patients was counted. The correlation between NRS2002 score and SF-36 score in patients with gastric cancer was analyzed. Results: Among 81 patients with gastric cancer, the nutritional risk occurred rate was 53.09%. Logistic multivariate regression analysis showed that age ≥60 years old (OR=1.657, 95%CI: 1.042-2.635), pain degree Ⅲ ~ Ⅳ degrees (OR=4.515, 95%CI: 1.656-12.310), gastrointestinal tract reaction Ⅲ ~ Ⅳ degrees (OR= 3.947, 95%CI: 1.599-9.743) were risk factor for gastric cancer patients with nutritional risk occurred (P＜0.05), but nutritional supplement (OR= 0.899, 95%CI: 0.846-0.955) was protective factor for gastric cancer patients with nutritional risk occurred (P＜0.05). The scores of emotional role function, physical role function, physical function, general health, mental health and physical pain in the nutritional risk group were lower than those in the no nutritional risk group, and the NRS2002 score was higher than that in the no nutritional risk group(P<0.05). The NRS2002 score of patients with gastric cancer was negatively correlated with emotional role function, physical role function, physical function, general health, mental health, and physical pain scores(P<0.05). The 3-month follow-up survival rate of the nutritional risk group was 95.35%, which was no difference compared with the 100% of the no nutritional risk group (P>0.05). The 12-month follow-up survival rate of the nutritional risk group was 79.07%, which was lower than the 94.74% of the no nutritional risk group(P<0.05). Conclusion: The patients with gastric cancer have a high incidence rate of nutritional risk, which is related to a variety of factors, nutritional risk can affect the quality of life and short-term prognosis, clinical need for timely nutritional risk assessment of patients with gastric cancer, and early intervention. |
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