| 兰小琼,易 勤,史修波,贺国容,佘冬华.超脉冲CO2点阵激光联合光子嫩肤治疗凹陷性痤疮瘢痕的疗效及影响因素分析[J].现代生物医学进展英文版,2021,(20):3950-3953. |
| 超脉冲CO2点阵激光联合光子嫩肤治疗凹陷性痤疮瘢痕的疗效及影响因素分析 |
| The Efficacy of Ultra-pulse CO2 Lattice Laser Combined with Photonic skin Rejuvenation in the Treatment of Depressed Acne Scars and Analysis of Influencing Factors |
| Received:April 01, 2021 Revised:April 23, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.20.030 |
| 中文关键词: 超脉冲CO2点阵激光 光子嫩肤 凹陷性痤疮瘢痕 疗效 影响因素 |
| 英文关键词: Ultra-pulse CO2 lattice laser Photonic skin rejuvenation Depressed acne scars Efficacy Influencing factors |
| 基金项目:四川省发育与再生重点实验室研究基金资助项目（SYS10-005） |
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| 中文摘要: |
| 摘要 目的：探讨超脉冲CO2点阵激光联合光子嫩肤治疗凹陷性痤疮瘢痕的疗效并分析其影响因素。方法：选取2018年7月到2020年8月于本院进行治疗的凹陷性痤疮瘢痕患者共计98例作为研究对象，所有患者均采用超脉冲CO2点阵激光联合光子嫩肤进行治疗，对患者治疗前后的症状积分以及瘢痕面积进行分析，同时根据患者治疗后的治疗效果将患者分为有效组以及对照组，利用二元Logistic回归分析超脉冲CO2点阵激光联合光子嫩肤治疗凹陷性痤疮瘢痕疗效的影响因素。结果：患者经过超脉冲CO2点阵激光联合光子嫩肤治疗后，症状积分以及瘢痕面积明显减小（P<0.05），治疗后3个月的总有效率达到79.59%。将治疗有效的患者作为有效组（n=78），将治疗无效的患者作为对照组（n=20），单因素分析结果表明，有效组患者的年龄、抑郁自评量表评分、焦虑自评量表评分以及病程明显低于对照组患者（P<0.05），有效组患者合并其它皮肤疾病的比例明显少于对照组患者（P<0.05）；二元Logistic回归分析结果显示：患者的年龄（OR=18.225，95%CI：6.805～31.589）、抑郁自评量表评分（OR=7.090，95%CI：2.430～21.148）、焦虑自评量表评分（OR=1.022，95%CI：1.008～1.036）、病程（OR=3.049，95%CI：1.346～6.184）以及合并其它皮肤疾病（OR=14.318，95%CI：5.234～18.595）为疗效的影响因素（P<0.05）。结论：采用超脉冲CO2点阵激光联合光子嫩肤对凹陷性痤疮瘢痕进行治疗，能够有效改善患者的症状，临床效果显著，患者的年龄、心理状态、病程以及合并其它皮肤疾病会影响超脉冲CO2点阵激光联合光子嫩肤对凹陷性痤疮瘢痕的治疗效果。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the efficacy of ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation in the treatment of depressed acne scars and analyze its influencing factors. Methods: A total of 98 patients with depressed acne scars who were treated in our hospital from July 2018 to August 2020 were selected as the research objects. All patients were treated with ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation, symptom scores and scar area of patients before and after treatment were analyzed. At the same time, the patients were divided into effective group and control group according to the treatment effect after treatment. Binary Logistic regression was used to analyze the influencing factors of the efficacy of ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation in the treatment of depressed acne scars. Results: After the patients were treated with ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation, the symptom scores and scar area were significantly reduced (P<0.05), and the total effective rate reached 79.59% at 3 months after treatment. The patients with effective treatment were regarded as the effective group (n=78), and the patients with ineffective treatment were regarded as the control group (n=20). The single factor analysis results showed that the age, self-rating depression scale score, self-rating anxiety scale score and disease course of patients of effective group were significantly lower than those of patients of control group P<0.05). The proportion of patients complicated with other skin diseases in effective group was significantly less than that in control group(P<0.05). Binary Logistic regression results showed that the patient's age (OR=18.225, 95%CI: 6.805～31.589), self-rating depression scale score (OR=7.090, 95%CI: 2.430～21.148), self-rating anxiety scale (OR=1.022, 95%CI: 1.008～1.036), disease course(OR=3.049, 95%CI: 1.346～6.184) and complicated with other skin diseases(OR=14.318, 95%CI: 5.234～18.595) were the influential factors of efficacy(P<0.05). Conclusion: The ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation in the treatment of depressed acne scars, can effectively improve the patient's symptoms, clinical effect is remarkable, the patient's age, mental state, disease course and complicated with other skin diseases will affect the treatment effect of ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation for depressed acne scars. |
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