| 陈 茜,王 伟,刘亚丽,张 璇,陈 菲.止哮平喘方联合子午流注针灸治疗老年支气管哮喘急性发作期患者的临床研究[J].现代生物医学进展英文版,2021,(19):3760-3764. |
| 止哮平喘方联合子午流注针灸治疗老年支气管哮喘急性发作期患者的临床研究 |
| Clinical Study of Zhixiao Pingchuan Prescription Combined with Ziwu Liuzhu Acupuncture in the Treatment of the Acute Attack Period of Elderly Bronchial Asthma |
| Received:February 23, 2021 Revised:March 18, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.19.033 |
| 中文关键词: 止哮平喘方 子午流注针灸 老年 支气管哮喘 急性发作期 |
| 英文关键词: Zhixiao Pingchuan prescription Ziwu Liuzhu acupuncture Elderly Bronchial asthma Acute attack period |
| 基金项目:陕西省中医药管理局科研项目（13-LC115） |
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| 中文摘要: |
| 摘要 目的：探讨止哮平喘方联合子午流注针灸治疗老年支气管哮喘急性发作期患者的临床效果。方法：选取2017年2月~2019年1月期间我院治疗的老年支气管哮喘急性发作期患者80例为研究对象。将所有患者根据随机数字表法分为对照组（n=40）和研究组（n=40），对照组给予常规西医治疗，研究组在对照组基础上给予止哮平喘方联合子午流注针灸治疗。比较两组患者临床疗效、肺功能、症状积分、免疫功能、不良反应。结果：研究组治疗后临床总有效率高于对照组（P<0.05）。治疗后研究组咳痰、呼吸困难、咳嗽、喘息等症状积分改善情况优于对照组（P<0.05）。两组患者治疗后CD3+、CD4+、CD4+/CD8+水平均升高，且研究组高于对照组（P<0.05）；CD8+水平降低，且研究组低于对照组（P<0.05）。两组患者治疗后第1秒用力呼气量占预计值的百分比（FEV1%pred）、用力肺活量占预计值的百分比（FVC%pred）、最大呼气峰流速占预计值的百分比（PEF%pred）均升高，且研究组高于对照组（P<0.05）。两组不良反应的发生率对比差异无统计学意义（P>0.05）。结论：止哮平喘方联合子午流注针灸可提高老年支气管哮喘急性发作期患者的治疗效果，改善其临床症状、肺功能以及免疫功能。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinical effect of Zhixiao Pingchuan prescription combined with Ziwu Liuzhu acupuncture in the treatment of the acute attack period of elderly bronchial asthma. Methods: 80 patients with acute attack period of elderly bronchial asthma who were admitted to our hospital from February 2016 to January 2019 were selected as the study subjects. All patients were divided into control group (n=40) and study group (n=40) according to random number table method, the control group was given conventional western medicine treatment, and the study group was given Zhixiao Pingchuan prescription combined with Ziwu Liuzhu acupuncture treatment on the basis of the control group. The clinical efficacy, pulmonary function, symptom score, immune function, adverse reactions of the patients in the two groups were compared. Results: The total effective rate of the study group was higher than that of the control group after treatment (P<0.05). The improvement of the scores of expectoration, dyspnea, cough and wheezing in the study group was better than that in the control group after treatment (P<0.05). The levels of CD3+, CD4+, CD4+/CD8+ in both groups were increased after treatment, and the study group were higher than those of the control group (P<0.05). The level of CD8+ was decreased, and the study group was lower than that of the control group (P<0.05). The percentage of forced expiratory volume of the first second in the predicted value (FEV1%pred), percentage of forced vital capacity in the predicted value (FVC%pred) , percentage of peak expiratory flow in the predicted value (PEF%pred) of the two groups were increased after treatment, and the study group were higher than those of the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Zhixiao Pingchuan prescription combined with Ziwu Liuzhu acupuncture can improve the therapeutic effect of elderly patients with acute attack period of bronchial asthma, and improve clinical symptoms, pulmonary function and immune function. |
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