| 赵树巧,牛学敏,石 蕾,杨宪武,薛 辉,张晓博,张新元.内镜下黏膜切除术治疗大肠息肉的临床疗效及术后出血的影响因素分析[J].现代生物医学进展英文版,2021,(18):3498-3501. |
| 内镜下黏膜切除术治疗大肠息肉的临床疗效及术后出血的影响因素分析 |
| Analysis of the Clinical Effect of Endoscopic Mucosal Resection in the Treatment of Large Intestine Polyp and the Influencing Factors of Postoperative Hemorrhage |
| Received:November 23, 2020 Revised:December 18, 2020 |
| DOI：10.13241/j.cnki.pmb.2021.18.021 |
| 中文关键词: 大肠息肉 内镜下黏膜切除术 疗效 生活质量 出血 影响因素 |
| 英文关键词: Large intestine polyp Endoscopic mucosal resection Efficacy Quality of life Hemorrhage Influencing factors |
| 基金项目:河北省医学科学研究重点计划项目(2018760)；石家庄市科学技术研究与发展计划项目(171462163 ) |
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| 中文摘要: |
| 摘要 目的：研究内镜下黏膜切除术（EMR）治疗大肠息肉的临床疗效及术后出血的影响因素。方法：将我院从2016年1月～2019年12月收治的大肠息肉患者500例纳入研究，所有患者均接受EMR治疗。分析其临床疗效以及术后出血发生情况，并对术后出血的影响因素实施单因素、多因素Logistic回归分析。结果：500例患者临床治疗总有效率为97.80%（489/500），术后出血发生例数为17例，出血发生率为3.40%（17/500）。治疗后患者各项生活质量评分均高于治疗前（均P<0.05）。经单因素分析发现：大肠息肉患者经EMR治疗后其切除息肉数、术后进食时间、息肉外观、息肉分叶均与术后出血有关（均P<0.05）；而年龄、性别、息肉部位以及病理类型均与术后出血无关（均P>0.05）。经多因素Logistic回归分析可得：切除息肉数≥4枚、术后48 h内进食、息肉外观潮红/糜烂以及息肉分叶均是大肠息肉患者经EMR治疗后出血的危险因素（均P<0.05）。结论：EMR治疗大肠息肉患者的临床疗效较佳，可改善其生活质量，其中切除息肉数、术后进食时间、息肉外观以及息肉分叶均和术后出血有关，值得临床关注。 |
| 英文摘要: |
| ABSTRACT Objective: To study the clinical efficacy of endoscopic mucosal resection (EMR) in the treatment of large intestine polyps and the influencing factors of postoperative bleeding. Methods: 500 patients with large intestine polyps admitted to our hospital from January 2016 to December 2019 were included in the study. All patients were treated with EMR. The clinical efficacy and postoperative bleeding were analyzed. Single factor and multivariate Logistic regression analyses were performed for the influencing factors of postoperative bleeding. Results: The total effective rate of clinical treatment was 97.80% (489/500). Postoperative bleeding occurred was 17 cases, and the incidence of bleeding was 3.40% (17/500). The quality of life scores of the patients after treatment were all higher than those before treatment (all P<0.05). Single factor analysis showed that the number of resected polyps, postoperative feeding time, appearance of polyps, and lobulation of polyps were all associated with bleeding after EMR treatment (all P<0.05). Age, sex, polyp site and pathological type were not associated with postoperative bleeding (all P>0.05). Multivariate Logistic regression analysis showed that the number of polyps resected ≥4 pieces, feeding within 48 days after surgery, polyp appearance flushing/erosion and polyp lobulation were risk factors for bleeding after EMR treatment (all P<0.05). Conclusion: EMR treatment of patients with colorectal polyps has a better clinical effect, which can improve their quality of life. The number of resected polyps, the postoperative feeding time, the appearance of the polyps and the lobulation of polyp are related to the postoperative bleeding, which deserves clinical attention. |
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