| 钟美英,唐征宇,刘 婷,王圆圆,邓雅戈,王永清.宫颈口开大2～3 cm应用间苯三酚对初产妇产后心理状态、血清应激反应指标和母婴结局的影响[J].现代生物医学进展英文版,2021,(16):3192-3195. |
| 宫颈口开大2～3 cm应用间苯三酚对初产妇产后心理状态、血清应激反应指标和母婴结局的影响 |
| Effects of Phloroglucinol on Postpartum Psychological Status, Serum Stress Response Indexes and Maternal and Infant Outcomes of Primiparas with Cervical Opening 2-3 cm |
| Received:January 28, 2021 Revised:February 23, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.16.039 |
| 中文关键词: 宫颈口开大2～3 cm 间苯三酚 初产妇 产后心理状态 应激反应 母婴结局 |
| 英文关键词: Cervical opening 2～3 cm Phloroglucinol Primiparas Postpartum psychological state Stress response Maternal and infant outcomes |
| 基金项目:湖南省中医药科研计划项目（2016154） |
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| 中文摘要: |
| 摘要 目的：观察宫颈口开大2～3 cm应用间苯三酚对初产妇产后心理状态、血清应激反应指标和母婴结局的影响。方法：对湖南中医药高等专科学校附属第一医院于2019年1月~2019年12月期间收治的初产妇200例进行研究，将其按照随机数字表法分为对照组和研究组，各为100例。对照组分娩期间给予常规处理，研究组则在对照组基础上注射间苯三酚，观察两组第一产程、第二产程、总产程，记录两组分娩后心理状况、母婴结局情况及不良反应发生率，对比两组宫颈口开大2～3 cm时、分娩后的应激反应指标。结果：研究组的第一产程、第二产程均短于对照组，从而使总产程明显缩短，组间对比差异有统计学意义（P<0.05）。研究组分娩后焦虑自评量表（SAS）与抑郁自评量表（SDS）评分均小于对照组，组间对比差异有统计学意义（P<0.05）。两组分娩后胰岛素、皮质醇及血糖水平均高于分娩前（P<0.05），但研究组胰岛素、皮质醇及血糖水平低于对照组（P<0.05）。两组产后出血率、新生儿窒息率组间对比差异无统计学意义（P>0.05），研究组的会阴裂伤（Ⅱ）率、助产分娩率低于对照组，正常分娩率高于对照组（P<0.05）。两组不良反应发生率对比无差异（P>0.05）。结论：初产妇宫颈口开大2～3 cm时应用间苯三酚，可减轻分娩时产生的应激反应，改善母婴结局，减轻产后抑郁焦虑情况，且安全性好。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effect of phloroglucinol on postpartum psychological status, serum stress response index and maternal and infant outcomes of primiparas with cervical opening 2-3 cm. Methods: 200 cases of primiparas who were admitted to the First Affiliated Hospital of Hunan College of traditional Chinese medicine from January 2019 to December 2019 were studied, they were randomly divided into control group and study group by the random number table method, 100 cases in each group. The control group was given routine treatment during delivery, while the study group was injected with phloroglucinol on the basis of the control group. The first stage of labor, the second stage of labor and the total stage of labor were observed in the two groups. The psychological status, maternal and infant outcomes and the incidence rate of adverse reactions after delivery in the two groups were recorded. The stress reaction indexes in the two groups were compared when the cervix opening 2 ~ 3 cm larger and after delivery. Results: The first stage of labor and the second stage of labor in the study group were shorter than those in the control group, which significantly shortened the total stage of labor, and the difference between the two groups was statistically significant (P<0.05). The scores of self rating Anxiety Scale (SAS) and self rating Depression Scale (SDS) in the study group after delivery were lower than those in the control group, and the difference was statistically significant (P<0.05). The levels of insulin, cortisol and blood glucose in the two groups after delivery were higher than those before delivery (P<0.05), but the levels of insulin, cortisol and blood glucose in the study group were lower than those in the control group (P<0.05). There were no significant differences in postpartum hemorrhage rate and neonatal asphyxia rate between the two groups (P>0.05). The perineal laceration(Ⅱ) rate and midwifery delivery rate in the study group were lower than those in the control group, and the normal delivery rate was higher than that in the control group (P<0.05). There was no difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Phloroglucinol should be used when the cervix opening 2 ~ 3 cm larger, which can reduce the stress reaction during delivery, improve the maternal and infant outcomes, and reduce postpartum depression and anxiety, and with good safety. |
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