| 徐正春,张好良,丁 会,张 磊,邓 桦,王 利.江苏省300例艾滋病人群联合检测 HCV、TP、HIV的结果分析[J].现代生物医学进展英文版,2021,(15):2921-2925. |
| 江苏省300例艾滋病人群联合检测 HCV、TP、HIV的结果分析 |
| Analysis on Results of Joint Detection of HCV, TP and HIV Among 300 AIDS Patients in Jiangsu Province |
| Received:December 23, 2020 Revised:January 17, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.15.025 |
| 中文关键词: 江苏省 HCV TP HIV 感染 |
| 英文关键词: Jiangsu Province HCV TP HIV Infection |
| 基金项目:江苏省医学青年人才培养项目（QNRC2016163） |
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| 中文摘要: |
| 摘要 目的：探究江苏省2017年至2019年度艾滋病哨点监测人群丙型肝炎病毒（Hepatitis C virus，HCV）、梅毒螺旋体（Treponema Pallidum，TP）以及人类免疫缺陷病毒（Treponema Pallidum，HIV）感染状况，以期为制定对应的疾患干预手段提供临床数据支撑。方法：严格按照《全国艾滋病哨点监测实施方案操作手册（2012版）》对入组的900例个体开展相关问卷调查，并对入组对象进行HCV、TP以及HIV感染血清学检测，分别统计3年总体感染情况、年度感染情况、不同年龄段人群感染情况以及合并感染情况。结果：（1）性工作者HCV、TP以及HIV感染率分别为3.00 %、4.00 %和9.00 %，吸毒人群感染率分别为13.00 %、73.00 %和13.00 %，孕产妇感染率分别为1.00 %、0.67 %和1.33 %，比较显示，吸毒人群HCV、TP以及HIV感染率明显高于其余两类人群（P<0.05）；（2）就各年度不同人群HCV、TP以及HIV感染率开展年度横向比较显示，不同年度不同人群的HCV、TP以及HIV感染率差异无统计学意义（P>0.05）；（3）针对不同年龄段不同人群的HCV、TP以及HIV感染率开展比较显示，吸毒人群中≥50岁HCV和HIV感染率明显高于其他年龄段（P<0.05），性工作者中18~20岁HIV感染率明显高于其他年龄段（P<0.05），其余差异无统计学意义（P>0.05）；（4）合并感染情况分析显示合并TP以及HIV感染率要高于其他合并感染。结论：吸毒人群是江苏省HCV、TP以及HIV感染高发群体，以≥50岁年龄段感染率最高，总体来看HCV、TP以及HIV感染率呈现逐年降低趋势，但仍应该加强对上述疾患的防控工作。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the infection status of Hepatitis C virus (HCV), Treponema Pallidum (TP) and Human Immunodeficiency Virus (Treponema Pallidum, HIV) in the AIDS sentinel surveillance population from 2017 to 2019 in Jiangsu Province in order to provide clinical data support for formulating corresponding disease intervention methods. Methods: A total of 900 individuals enrolled in the group were asked to fill in related questionnaires according to the "National AIDS Sentinel Surveillance Implementation Program Operation Manual (2012 Edition)". The enrolled subjects questioned were examined by HCV, TP and HIV infection serological tests. 3 years of overall infection status, annual infection status, infection status of people in the different age groups, and co-infection status were counted. Results: (1) The HCV, TP, and HIV infection rates of sex workers were 3.00%, 4.00 %, and 9.00 %, respectively, the drug users' infection rates were 13.00 %, 73.00 %, and 13.00 %, and the maternal infection rates were 1.00 %, 0.67 % and 1.33 %；the infection rates of HCV, TP and HIV among drug users were significantly higher than those of the other two groups(P<0.05). (2) Annual horizontal comparison of HCV, TP and HIV infection rates among different people in each year showed that there was little difference in HCV, TP and HIV infection rates among different people in different years(P>0.05). (3) Comparison of HCV, TP, and HIV infection rates among different people at different age groups shows that the infection rate of HCV and HIV among drug users ≥50 years old was significantly higher than those among the other age groups (P<0.05); the HIV infection rate among sex workers was significantly higher than that among the other age groups(P<0.05). The remaining differences were not statistically significant (P>0.05). (4) Co-infection analysis shows that combined TP and HIV infection rates were higher than other combined infection. Conclusion: Conclusion: Drug users are the high-incidence group of HCV, TP and HIV infection in Jiangsu Province, with the highest infection rate in the age group of ≥50 years old. Overall, the infection rate of HCV, TP and HIV is decreasing year by year, but the prevention and control of the above diseases should still be strengthened. |
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