| 韦 斌,钟晓刚,麦 威,黄顺荣,牙韩清,王晓通.不同体质量指数对腹腔镜结直肠癌切除术患者临床疗效和远期预后的影响[J].现代生物医学进展英文版,2021,(15):2902-2905. |
| 不同体质量指数对腹腔镜结直肠癌切除术患者临床疗效和远期预后的影响 |
| Effects of Different Body Mass Index on Clinical Efficacy and Long-term Prognosis of Patients Undergoing Laparoscopic Colorectal Cancer Resection |
| Received:January 26, 2021 Revised:February 21, 2021 |
| DOI：10.13241/j.cnki.pmb.2021.15.021 |
| 中文关键词: 腹腔镜 结直肠癌切除术 体质量指数 临床疗效 远期预后 |
| 英文关键词: Laparoscopy Colorectal cancer resection Body mass index Clinical efficacy Long-term prognosis |
| 基金项目:广西壮族自治区卫生和计划生育委员会自筹经费科研课题（Z2015363，Z2016580） |
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| 中文摘要: |
| 摘要 目的：研究不同体质量指数（BMI）对腹腔镜结直肠癌切除术患者临床疗效和远期预后的影响。方法：将从2014年1月～2016年1月于我院接受腹腔镜结直肠癌切除术治疗的110例患者纳入研究。将所有受试者根据BMI的差异分作正常组（18.6 kg/m2≦BMI<23.0 kg/m2）35例、超重组（23.0 kg/m2≦BMI<25.0 kg/m2）53例、肥胖组（BMI≧25.0 kg/m2）22例。分析三组患者各项基线资料，临床疗效，术后并发症发生情况，远期预后等方面的差异。结果：三组患者各项基线资料比较差异均不明显（均P＞0.05）。肥胖组手术时长为（268.01±36.14）min，均明显高于正常组、超重组的（211.73±30.56）min、（224.12±34.87）min（均P＜0.05）；三组术中失血量、肛门排气时间以及住院康复时间对比均不明显（均P＞0.05）。三组患者术后肺部感染、下肢静脉血栓、切口感染以及吻合口出血发生率对比均不明显（均P＞0.05）。正常组5年生存率为45.71%（16/35），超重组5年生存率为47.17%（25/53），肥胖组5年生存率为45.45%（10/22），三组比较差异无统计学意义（均P＞0.05）。结论：不同BMI对腹腔镜结直肠癌切除术患者的手术时长具有一定影响，但和远期预后无关，值得临床重点关注。 |
| 英文摘要: |
| ABSTRACT Objective: To study the effects of different body mass index (BMI) on the clinical efficacy and long-term prognosis of patients undergoing laparoscopic colorectal cancer resection. Methods: From January 2014 to January 2016, 110 patients who underwent laparoscopic colorectal cancer resection in our hospital were included in this study. All the subjects were divided into normal group (18.6 kg/m2≦BMI<23.0 kg/m2) with 35 cases, overweight group (23.0 kg/m2≦BMI<25.0 kg/m2) with 53 cases and obesity group (BMI≧25.0 kg/m2) with 22 cases according to the differences in BMI. The differences in baseline data, clinical efficacy, postoperative complications and long-term prognosis of the three groups were analyzed. Results: There were no significant differences in baseline data among the three groups (all P>0.05). The operative duration of obesity group was (268.01±36.14) min, which was significantly higher than that of normal group and overweight group of (211.73±30.56) min, (224.12±34.87) min (all P<0.05). There were no significant differences in intraoperative blood loss, anal exhaust time and length of hospital recovery between the three groups (all P>0.05). The incidence of postoperative pulmonary infection, lower limb venous thrombosis, incision infection and anastomotic bleeding were not significantly compared among the three groups(all P>0.05). The 5-year survival rate in the normal group was 45.71% (16/35), the 5-year survival rate in the overweight group was 47.17% (25/53), and the 5-year survival rate in the obesity group was 45.45% (10/22), without statistical significance among the three groups(all P＞0.05). Conclusion: Different BMI has a certain influence on the operative duration of patients undergoing laparoscopic colorectal cancer resection, but it is not related to the long-term prognosis, which deserves clinical attention. |
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