| 朱泽忠,刘晓芳,牟 燕,何玉春,何 佳.聚焦超声消融治疗子宫小肌瘤的疗效评价[J].现代生物医学进展英文版,2021,(13):2526-2530. |
| 聚焦超声消融治疗子宫小肌瘤的疗效评价 |
| Evaluation of the Therapeutic Effect of Focused Ultrasound Ablation in the Treatment of Uterine Small Fibroids |
| Received:November 28, 2020 Revised:December 23, 2020 |
| DOI：10.13241/j.cnki.pmb.2021.13.026 |
| 中文关键词: 聚焦超声消融手术 无症状 子宫小肌瘤 缩小率 增长率 妊娠率 |
| 英文关键词: Focused ultrasound ablation Asymptomatic Uterine small fibroids Reduction rate Growth rate Pregnancy rate |
| 基金项目:四川省卫生健康委员会科研项目（普及应用项目）（20PJ283） |
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| 中文摘要: |
| 摘要 目的：探讨聚焦超声消融治疗无症状子宫小肌瘤的临床价值。方法：采用对照回顾性研究，将2011年03月至2018年03月在遂宁市中心医院妇科收治入院行聚焦超声消融治疗的无症状的子宫小肌瘤患者设置为治疗组，将同期未经任何治疗的门诊随访的无症状子宫小肌瘤患者设置为对照组，比较两组在6个月、12个月、18个月、24个月后子宫肌瘤的体积变化、是否出现临床症状及妊娠情况。结果：治疗组在聚焦超声消融治疗后6个月、12个月、18个月、24个月，随着时间的推移，子宫小肌瘤的体积较治疗前逐渐缩小，均未出现临床症状；对照组子宫小肌瘤的体积逐渐增大，并出现临床症状；治疗组和对照组24个月内的妊娠率分别为17.48%和8.42%,比较两组差异有统计学意义(P＜0.05)。聚焦超声消融治疗后无严重并发症发生。结论：对于孕龄期有生育要求的黏膜下或肌壁间的无症状子宫小肌瘤患者，可行聚焦超声消融手术缩小病灶，维持子宫腔的正常形态，避免或延迟临床症状的出现，提高妊娠率。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical value of focused ultrasound ablation (FUA) in the treatment of asymptomatic uterine small fibroids. Methods: A retrospective study was conducted to analyze the treatment results of asymptomatic patients with uterine small fibroids that were admitted to the Department of Gynecology of Suining Central Hospital and were treated with FUA between March 2011 and March 2018. We also followed up the asymptomatic patients with uterine small fibroids who presented in the outpatient clinic without any treatment of the same period. The volume changes of uterine fibroids, symptoms and pregnancy outcomes at 6 months, 12 months, 18 months, and 24 months after FUA were recorded and further compared with the patients who didn't have any treatment. Results: In the treatment group, 6 months, 12 months, 18 months, and 24 months after FUA treatment, the volume of uterine small fibroids gradually decreased compared with the volume before FUA treatment, and no clinical symptoms appeared. The average volume of uterine small fibroids in the control group gradually increased, and clinical symptoms appeared. The pregnancy rates of the treatment group and the control group within 24 months was 17.48% and 8.42%, respectively. A significant difference between the two groups was observed(P＜0.05). No major adverse effects were observed. Conclusion: For patients with asymptomatic uterine submucous small fibroids or intramural small fibroids during gestational age, FUA can be used to reduce the size of fibroids, maintain the normal shape of the uterine cavity, reduce the risk of occurrence of clinical symptoms, and increase the pregnancy rates. |
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