| 刘绍辉,王青杰,赵立涵,李月廷,王 海.前列腺炎患者的血清TPSA表达与微波治疗预后的相关性[J].现代生物医学进展英文版,2021,(11):2081-2084. |
| 前列腺炎患者的血清TPSA表达与微波治疗预后的相关性 |
| Correlation of Serum TPSA Expression with Prognosis in Patients with Prostatitis |
| Received:October 02, 2020 Revised:October 22, 2020 |
| DOI：10.13241/j.cnki.pmb.2021.11.018 |
| 中文关键词: 微波 前列腺炎 国际前列腺症状评分 总前列腺特异性抗原 相关性 |
| 英文关键词: Microwave Prostatitis International prostate symptom score Total prostate-specific antigen Correlation |
| 基金项目:国家卫生计生委医药卫生科技发展项目（W2015CAE173） |
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| 中文摘要: |
| 摘要 目的：探讨前列腺炎患者的血清总前列腺特异性抗原(otal Prostate specific antigten，TPSA)表达与微波治疗预后的相关性。方法：2018年2月至2019年8月选择在北京市中西医结合医院（本院）诊治的78例前列腺炎患者，根据随机数字表法分为微波组与对照组，各39例，对照组给予盐酸坦索罗辛治疗，微波组在对照组治疗的基础上给予微波治疗，两组都治疗观察4 w，记录血清TPSA表达变化情况并进行相关性分析。结果：所有患者都完成治疗，治疗过程中无不良反应发生。微波组的总有效率为97.4 %，显著高于对照组的84.6 %(P<0.05)。两组治疗后的国际前列腺症状评分(International Prostate Symptom Score，IPSS)低于治疗前，微波组低于对照组，对比差异都有统计学意义(P<0.05)。两组治疗后血清TPSA值低于治疗前，微波组低于对照组，对比差异都有统计学意义(P<0.05)。在78例患者中，直线相关分析显示患者预后有效率与微波治疗、IPSS评分、TPSA值、临床分期、病程等显著相关(P<0.05)。结论：微波治疗前列腺炎能促进缓解患者的临床症状，提高治疗效果，抑制血清TPSA的表达，血清TPSA表达与微波治疗预后有显著相关性。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the correlation between serum TPSA expression and prognosis of microwave therapy in patients with prostatitis. Methods: From February 2018 to August 2019, 78 cases of patients with prostatitis who were treated in Beijing Hospital of Integrated Traditional Chinese and Western Medicine (our hospital )were selected as the research subjects and were divided into microwave group and control group with 39 cases in each groups. The control group was given tamsulosin hydrochloride, the microwave group was given microwave treatment on the basis of the control group. Two groups were treated and observed for 4 weeks. The changes in serum total prostate specific antigen (TPSA) expression were recorded and correlated analysis were performed. Results: All patients were completed the treatment and there were no adverse reactions occurred during the treatment. The total effective rates in the microwave group was 97.4 %, which was significantly higher than the control group of 84.6 % (P<0.05). After treatment, the International Prostate Symptom Score (IPSS) of the two groups were lower than before treatment, and the microwave group were lower than that of the control group, and compared the difference were statistically significant (P<0.05). The serum TPSA value in the two groups after treatment were lower than in the microwave group before treatment, and the comparison were statistically significant (P<0.05). In the 78 patients, linear correlation analysis showed that the prognosis effectiveness of patients were significantly related to microwave treatment, IPSS score, TPSA value, clinical stage, and disease duration (P<0.05). Conclusion: Microwave treatment of prostatitis can promote the relief of clinical symptoms, improve the treatment effect, and inhibit the expression of serum TPSA. The expression of serum TPSA are significantly correlated with the prognosis of microwave treatment. |
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