| 徐 亮,郑 艳,江磊磊,庄 丽,何 帆.重复经颅磁刺激联合阿普唑仑治疗失眠症伴焦虑患者的效果分析[J].现代生物医学进展英文版,2021,(8):1533-1536. |
| 重复经颅磁刺激联合阿普唑仑治疗失眠症伴焦虑患者的效果分析 |
| Analysis of the Efficacy of Repeated Transcranial Magnetic Stimulation Combined with Alprazolam in the Treatment of Insomnia with Anxiety |
| Received:July 02, 2020 Revised:July 26, 2020 |
| DOI：10.13241/j.cnki.pmb.2021.08.029 |
| 中文关键词: 重复经颅磁刺激 阿普唑仑 失眠症 焦虑 |
| 英文关键词: Repeated Transcranial Magnetic Stimulation Alprazolam Insomnia Anxiety |
| 基金项目:江苏省中医药管理局科技项目（JD201810） |
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| 中文摘要: |
| 摘要 目的：研究重复经颅磁刺激以及阿普唑仑联用治疗失眠症伴焦虑患者的效果。方法：选择2015年1月～2019年12月我院神经内科收治的81例失眠症伴焦虑患者，将其随机分为两组。对照组每晚在睡前30 min服用阿普唑仑0.8 mg，观察组联用重复经颅磁刺激。比较两组的临床疗效，治疗前后焦虑评分、生活质量和睡眠质量评分的变化。结果：治疗后，观察组的有效率为95.00 %，明显高于对照组(73.17 %，P<0.05)；两组焦虑评分均较治疗前明显降低(P<0.05)，心理领域、社会领域、环境领域和生理领域评分均较治疗前明显升高(P<0.05)，且观察组的焦虑评分和心理领域、社会领域、环境领域、生理领域评分明显优于对照组(P<0.05)；两组的睡眠持续性、主观睡眠质量、睡眠障碍、日间功能、睡眠潜伏期、安眠药物和入睡时间评分均较治疗前明显升高(P<0.05)，且观察组以上指标均明显高于对照组(P<0.05)。结论：重复经颅磁刺激以及阿普唑仑联用治疗失眠症伴焦虑患者的效果明显优于单用阿普唑仑治疗，其能有效减轻其焦虑程度，提高患者生活质量及睡眠质量。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of repeated transcranial magnetic stimulation combined with alprazolam in the treatment of insomnia and anxiety. Methods: Eighty-one patients with insomnia and anxiety who were treated in the department of neurology in our hospital's from January 2015 to December 2019 were selected and randomly divided into two groups. The control group took 0.8 mg of alprazolam 30 min before going to bed every night, and the observation group was combined with repeated transcranial magnetic stimulation. Compare the clinical efficacy changes in anxiety score, quality of life and sleep quality score before and after treatment of the two groups. Results: After treatment, the effective rate of observation group was 95.00 %, which was significantly higher than that of the control group (73.17 %, P<0.05). The anxiety scores of the two groups were significantly lower than before treatment (P<0.05), and the scores of psychological, social, environmental and physiological fields were significantly higher than those before treatment (P<0.05), and the observation group's anxiety scores and psychological, social, environmental, and physiological fields were significantly better than the control group (P<0.05). The scores of sleep persistence, subjective sleep quality, sleep disorders, daytime function, sleep latency, sleeping drugs and time to fall asleep fall asleep were significantly higher than before treatment(P<0.05), and the above indicators in the above indicators in the observation group were significantly higher than those in the control group(P<0.05). Conclusion: The effect of repeated transcranial magnetic stimulation and alprazolam in the treatment of patients with insomnia and anxiety was significantly better than that of alprazolam alone, which could effectively reduce their anxiety and improve the quality of life and sleep quality of patients. |
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