| 张乐琪,谭 蕾,孙 聪,邓春妮,陶 洪.单次与重复多次根管疏通填充对牙体牙髓病患者疼痛程度、咀嚼功能及炎性因子水平的影响[J].现代生物医学进展英文版,2020,(23):4497-4500. |
| 单次与重复多次根管疏通填充对牙体牙髓病患者疼痛程度、咀嚼功能及炎性因子水平的影响 |
| Effects of Single and Repeated Root Canal Dredging and Filling on Pain, Masticatory Function and Inflammatory Factors in Patients with Dental Pulp Disease |
| Received:March 23, 2020 Revised:April 18, 2020 |
| DOI：10.13241/j.cnki.pmb.2020.23.021 |
| 中文关键词: 单次根管疏通填充 重复多次根管疏通填充 牙体牙髓病 疼痛程度 咀嚼功能 炎性因子 |
| 英文关键词: Single root canal dredging and filling Repeated root canal dredging and filling Dental pulp disease Degree of pain Masticatory function Inflammatory factors |
| 基金项目:陕西省卫生和计划生育委员会科技计划项目（2017D2179） |
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| 中文摘要: |
| 摘要 目的：探讨单次与重复多次根管疏通填充对牙体牙髓病患者疼痛程度、咀嚼功能及炎性因子水平的影响。方法：选取我院收治的119例牙体牙髓病患者，按照乱数表法将患者分为A组（n=59，重复多次根管疏通填充治疗）、B组（n=60，单次根管疏通填充治疗）。比较两组患者临床疼痛程度、总有效率、咀嚼功能及炎性因子水平，记录两组并发症发生情况。结果：B组治疗2周后的临床总有效率为93.33%（56/60），高于A组的74.58%（44/59）（P<0.05）。治疗2周后两组患者咬合力、咀嚼效率升高，且B组高于A组（P<0.05）；两组患者治疗2周后牙龈指数、视觉疼痛模拟评分法（VAS）评分均下降，且B组低于A组（P<0.05）。两组患者治疗2周后血清白介素-6（IL-6）、肿瘤坏死因子-?琢（TNF-?琢）、C反应蛋白（CRP）水平均降低，且B组低于A组（P<0.05）。B组术后并发症发生率低于A组（P<0.05）。结论：采用单次根管疏通填充治疗可有效改善牙体牙髓病患者临床症状及炎性因子水平，还可降低术后并发症发生率，疗效确切。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effects of single and repeated root canal dredging and filling on the pain degree, masticatory function and inflammatory factors of patients with dental pulp disease. Methods: A total of 119 patients with dental pulp disease who were admitted to our hospital from February 2017 to May 2019 were selected, they were randomly divided into group A (n=59, repeated root canal dredging and filling treatment) and group B (n=60, single root canal dredging and filling treatment). The pain degree, total effective rate, masticatory function and inflammatory factor level of the two groups were compared, and the complications of the two groups were recorded. Results: The total clinical effective rate of group B was 93.33% (56/60), which was higher than that of group A 74.58% (44/59) (P<0.05). 2 weeks after treatment, the biting force and chewing efficiency of the two groups increased, and those of group B were higher than those of group A (P<0.05). 2 weeks after treatment, the gingival index and visual pain simulation score (VAS) of the two groups decreased, and those of group B were lower than those of group A (P<0.05). The serum levels of interleukin -6 (IL-6), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP) of the two groups decreased at 2 weeks after treatment, and the levels of group B were lower than those of group A (P<0.05). The incidence of postoperative complications of group B was lower than that of group A (P<0.05). Conclusion: Single root canal dredging and filling can effectively improve the clinical symptoms of patients with dental pulp disease, with definite curative effect. At the same time, it can also reduce the level of inflammatory factors and the incidence of postoperative complications. It has certain clinical application value. |
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