| 王文娟,崔更力,李 艳,王 莹,曹春艳,倪 家.疏风解毒胶囊辅以综合管理干预对慢性阻塞性肺疾病患者呼吸及运动功能的影响[J].现代生物医学进展英文版,2020,(23):4432-4435. |
| 疏风解毒胶囊辅以综合管理干预对慢性阻塞性肺疾病患者呼吸及运动功能的影响 |
| Effects of Shufeng Jiedu Capsule Supplemented with Comprehensive Management Intervention on Respiratory and Motor Function Improvement in Chronic Obstructive Pulmonary Disease Patients |
| Received:May 25, 2020 Revised:June 21, 2020 |
| DOI：10.13241/j.cnki.pmb.2020.23.007 |
| 中文关键词: 疏风解毒胶囊 慢性阻塞性肺疾病 6分钟步行实验 呼吸困难指数评分 综合管理干预 |
| 英文关键词: Shufeng jiedu capsule Chronic obstructive pulmonary disease 6 MWT MRC score Integrated management intervention |
| 基金项目:北京市科技计划项目（D161100000416015） |
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| 中文摘要: |
| 摘要 目的：探讨疏风解毒胶囊辅以综合管理干预对慢性阻塞性肺疾病（COPD）患者呼吸及运动功能改善的影响。方法：选取2018年10月-2019年10月到我院进行治疗的COPD患者84例作为研究对象，随机数字表法分为两组，患者均使用疏风解毒胶囊进行治疗，对照组（n=42）予以常规干预，试验组（n=42）进行综合管理干预。对比两组患者的临床治疗有效率、肺功能改善情况、肺功能指标、呼吸困难指数（MRC）评分以及6分钟步行实验（6MWT）结果。结果：试验组的临床治疗有效率高于对照组（P<0.05）。干预后，两组动脉血二氧化碳分压（PaCO2）和MRC评分较干预前降低（P<0.05），动脉血氧分压（PaO2）、动脉血氧饱和度（SaO2）、第1秒用力呼气容器（FEV1）、用力肺活量（FVC）、FEV1/FVC均较干预前升高（P<0.05），6MWT距离较干预前增加（P<0.05），且试验组上述指标改善情况更优（P<0.05）。结论：疏风解毒胶囊辅以综合管理干预可提高COPD患者的临床治疗效果，改善其肺功能，可有效缓解呼吸困难，提升运动强度，值得在临床上应用与推广。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of shufeng jiedu capsule supplemented with comprehensive management on the respiratory and motor functions in Chronic obstructive pulmonary disease(COPD) patients. Methods: A total of 84 COPD patients treated in our hospital from October 2018 to October 2019 were selected as the study object. which were divided into two groups by random number table method, all the patients were treated with shufeng jiedu capsules, the control group(n=41) was routinely treated with intervention, and the experimental group(n=41) was treated with comprehensive management intervention.The clinical effective rate, pulmonary function improvement, pulmonary function index, dyspnea index (MRC) score and 6-minute walk test (6MWT) results of the two groups were compared. Results: The clinical effective rate of the experimental group was higher than that of the control group (P<0.05). After the intervention, PaCO2 and MRC scores of the two groups were lower than those before intervention (P<0.05), PaO2, SaO2, FEV1, FVC, FEV1 / FVC were increased (P<0.05), 6MWT distance was increased (P<0.05) in the experimental group. The condition was better (P<0.05). Conclusion: Shufeng jiedu capsule supplemented comprehensive management intervention can improve the clinical treatment effect of COPD patients, improve their lung function, effectively relieve dyspnea and enhance exercise intensity, which is worthy of clinical application and promotion. |
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