| 王 磊,麻 松,朱继超,张 舵,崔 维.单侧与双侧穿刺入路PKP术对骨质疏松性胸腰椎压缩骨折患者手术效果、生活质量以及血清应激因子的影响[J].现代生物医学进展英文版,2020,(14):2690-2693. |
| 单侧与双侧穿刺入路PKP术对骨质疏松性胸腰椎压缩骨折患者手术效果、生活质量以及血清应激因子的影响 |
| The Effect of Unilateral and Bilateral Puncture Approach PKP on the Operative Effect, Quality of Life and Serum Stress Factors in Patients with Osteoporotic Thoracolumbar Compression Fracture |
| Received:March 03, 2020 Revised:March 27, 2020 |
| DOI：10.13241/j.cnki.pmb.2020.14.019 |
| 中文关键词: 单侧穿刺入路 双侧穿刺入路 经皮椎体后凸成形术 骨质疏松性胸腰椎压缩骨折 手术效果 生活质量 应激因子 |
| 英文关键词: Unilateral puncture approach Bilateral puncture approach Percutaneous kyphoplasty Osteoporotic thoracolumbar compression fracture Operative effect Quality of life Stress factors |
| 基金项目:首都卫生发展科研专项项目（2016-1-4096） |
| Author Name | Affiliation | E-mail | | WANG Lei | Department of Spinal Surgery, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, 100070, China | w_8963869@163.com | | MA Song | Department of Spinal Surgery, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, 100070, China | | | ZHU Ji-chao | Department of Spinal Surgery, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, 100070, China | | | ZHANG Tuo | Department of Spinal Surgery, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, 100070, China | | | CUI Wei | Department of Spinal Surgery, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, 100070, China | |
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| 中文摘要: |
| 摘要 目的：探讨单侧与双侧穿刺入路经皮椎体后凸成形术（PKP）对骨质疏松性胸腰椎压缩骨折（OVCF）患者手术效果、生活质量以及血清应激因子的影响。方法：回顾性选取2016年7月~2019年7月期间我院接收的行PKP的OVCF患者83例。根据入路方式的不同分为A组（n=41，单侧穿刺入路）和B组（n=42，双侧穿刺入路），对比两组患者围术期指标、影像学指标、视觉模拟评分法（VAS）评分、Oswestry腰椎功能障碍指数（ODI）评分、健康调查生活质量量表（SF-36）评分、血清应激因子以及并发症发生情况。结果：A组手术时间短于B组，骨水泥用量、术中透视次数少于B组（P<0.05）。两组术后6个月VAS评分、ODI评分降低，SF-36评分升高（P<0.05）。两组术后3d去甲肾上腺素（NE）、肾上腺素（E）、皮质醇（Cor）均升高，但A组低于B组（P<0.05）。两组术后6个月椎体前缘高度、后凸Cobb角均升高（P<0.05）。两组并发症发生率比较差异无统计学意义（P>0.05）。结论：单侧穿刺入路PKP可获得与双侧穿刺入路PKP相当的治疗效果和安全性，同时可缩短手术时间，减少骨水泥用量及术中透视次数，减轻机体应激反应。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of unilateral and bilateral puncture approach percutaneous kyphoplasty (PKP) on the operative effect, quality of life and serum stress factors in patients with osteoporotic thoracolumbar compression fracture. Methods: 83 patients with OVCF who were received in our hospital from July 2016 to July 2019 were selected retrospectively. According to the different approaches, the patients were divided into the group A (n=41, unilateral puncture approach) and group B (n=42, bilateral puncture approach). Perioperative indexes, imaging indexes, visual analogue scale (VAS) score, Oswestry lumbar dysfunction index (ODI) score, quality of life scale (SF-36) score, serum stress factors and complications were compared between the two groups. Results: The operation time of group A was shorter than that of group B, the amount of bone cement and the times of intraoperative fluoroscopy were less than those of group B (P<0.05). The scores of VAS and ODI decreased, and SF-36 increased in the two groups at 6 months after operation (P<0.05). The norepinephrine (NE), epinephrine (E) and cortisol (Cor) were increased in both groups at 3d after operation, but the levels in group A were lower than those in group B (P<0.05). The anterior height of vertebral body and convex Cobb angle increased in both groups at 6 months after operation (P<0.05). There was no significant difference in the incidence of complications between the two groups (P>0.05). Conclusion: Unilateral puncture approach PKP can achieve the same therapeutic effect and safety as that bilateral puncture approach PKP, and it can shorten the operation time, reduce the amount of bone cement and the times of intraoperative fluoroscopy, and reduce the stress response of the body. |
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