| 杨 旭,张志利,徐幼苗,董 蕊,李丽梅,刘 悦,宛春甫.双极脉冲射频抑制神经根型颈椎病患者围手术期炎症因子释放的价值[J].现代生物医学进展英文版,2020,(12):2355-2358. |
| 双极脉冲射频抑制神经根型颈椎病患者围手术期炎症因子释放的价值 |
| The Value of Bipolar Pulse Radiofrequency Suppression for Perioperative Inflammatory Factor Release in Patients with Cervical Spondylotic Radiculopathy |
| Received:October 22, 2019 Revised:November 28, 2019 |
| DOI：10.13241/j.cnki.pmb.2020.12.034 |
| 中文关键词: 双极脉冲射频 神经根型颈椎病 炎症因子 颈椎功能 并发症 疗效 |
| 英文关键词: Bipolar pulse radiofrequency Cervical spondylotic radiculopathy Inflammatory factors Cervical function Complications Curative effect |
| 基金项目:河北省医学科学研究项目（20180525）；秦皇岛市科学技术研究与发展计划项目（201805A169） |
| Author Name | Affiliation | E-mail | | YANG Xu | Department of Pain, Qinhuangdao First Hospital Affiliated to Hebei Medical University, Qinhuangdao, Hebei, 066000, China | 274146891@qq.com | | ZHANG Zhi-li | Department of Pain, Qinhuangdao First Hospital Affiliated to Hebei Medical University, Qinhuangdao, Hebei, 066000, China | | | XU You-miao | Department of Pain, Qinhuangdao First Hospital Affiliated to Hebei Medical University, Qinhuangdao, Hebei, 066000, China | | | DONG Rui | Department of Pain, Qinhuangdao First Hospital Affiliated to Hebei Medical University, Qinhuangdao, Hebei, 066000, China | | | LI Li-mei | Department of Pain, Qinhuangdao First Hospital Affiliated to Hebei Medical University, Qinhuangdao, Hebei, 066000, China | | | LIU Yue | Department of Pain, Qinhuangdao First Hospital Affiliated to Hebei Medical University, Qinhuangdao, Hebei, 066000, China | | | WAN Chun-fu | Department of Pain, Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050011, China | |
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| 中文摘要: |
| 摘要 目的：探讨双极脉冲射频抑制神经根型颈椎病患者围手术期炎症因子释放的价值。方法：2017年2月到2019年4月选择在本院进行诊治的74例神经根型颈椎病患者，根据随机数字表法分为观察组与对照组各37例。对照组给予神经根阻滞注射治疗，观察组给予颈椎神经根双极脉冲射频治疗，观察两组术后14 d的疗效及并发症发生情况，比较两组手术前后的日本骨科协会(JOA)评分和白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平。结果：术后14 d观察组的总有效率为97.30%，高于对照组的81.08%(P<0.05)。两组术后14 d的JOA评分均显著高于术前1d(P<0.05)；与对照组相比，观察组术后14 d的JOA评分较高(P<0.05)。观察组术后14 d的感觉减退、出血、感染、神经损伤并发症总发生率为5.40%，低于对照组的27.04%(P<0.05)。两组术后14 d的血清IL-6和TNF-α水平均显著低于术前1 d(P<0.05)；与对照组相比，观察组术后14 d的炎症因子水平均较低(P<0.05)。结论：双极脉冲射频能抑制神经根型颈椎病患者围手术期的炎症因子释放，从而改善患者的颈椎功能，减少并发症的发生，提高治疗疗效。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the value of bipolar pulse radiofrequency suppression for perioperative inflammatory factor release in patients with cervical spondylotic radiculopathy. Methods: 74 cases of cervical spondylotic radiculopathy treated in our hospital from February 2017 to April 2019 were selected, they were divided into observation group and control group according to the random number table method, 37 cases in each group. The control group were given nerve root block injection therapy, and the observation group were given radiofrequency treatment of cervical nerve root bipolar pulse. The curative effect and complications of the two groups on 14 days after operation were observed, the Japan orthopaedic association (JOA) scores and the levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) before and after operation were compared between the two groups. Results: The total effective rate of the observation group was 97.30% on the 14 days after operation, which was higher than 81.08% of the control group (P<0.05). The JOA scores on the 14 days after operation in both groups were significantly higher than that on the 1 day before operation (P<0.05). Compared with the control group, the JOA scores on the 14 days after operation of the observation group were higher than that of the control group (P<0.05). The total incidence of sensory decline, hemorrhage, infection, nerve injury complications of the observation group was 5.40% 14 days after operation, which were lower than 27.04% of the control group (P<0.05). The levels of serum IL-6, TNF-α on the 14 days after operation in both groups were significantly lower than that on the 1 day before operation (P<0.05). Compared with the control group, the levels of inflammatory factors on the 14 days after operation of the observation group were lower than that of the control group (P<0.05). Conclusion: Bipolar pulse radiofrequency can inhibit the release of inflammatory factors in perioperative period of patients with cervical spondylotic radiculopathy, thus improving cervical function, reduce the incidence of complications and improve the therapeutic effect. |
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