| 刘 欢,朱述阳,于海容,洪 倩,潘 倩.CRP、PCT、WBC联合检测对中老年社区获得性肺炎的诊断效果[J].现代生物医学进展英文版,2020,(11):2094-2097. |
| CRP、PCT、WBC联合检测对中老年社区获得性肺炎的诊断效果 |
| Diagnostic Efficacy of Combined Detection of CRP, PCT and WBC in Elderly Patients with Community Acquired Pneumonia |
| Received:December 01, 2019 Revised:December 23, 2019 |
| DOI：10.13241/j.cnki.pmb.2020.11.019 |
| 中文关键词: C 反应蛋白 降钙素原 白细胞 中老年社区获得性肺炎 |
| 英文关键词: C-reactive protein Procalcitonin White blood cell Elderly community-acquired pneumonia |
| 基金项目:国家自然科学基金青年基金项目（81500951） |
| Author Name | Affiliation | E-mail | | LIU Huan | 1 Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China
2 Department of Respiratory, Huaihai Hospital, Xuzhou Medical University, Xuzhou, Jiangsu, 221000, China | lhshitou2019@163.com | | ZHU Shu-yang | Department of Respiratory, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221000, China | | | YU Hai-rong | Department of Respiratory, Huaihai Hospital, Xuzhou Medical University, Xuzhou, Jiangsu, 221000, China | | | HONG Qian | Department of Pediatrics, Huaihai Hospital, Xuzhou Medical University, Xuzhou, Jiangsu, 221000, China | | | PAN Qian | Department of Clinical Laboratory, Huaihai Hospital, Xuzhou Medical University, Xuzhou, Jiangsu, 221000, China | |
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| 中文摘要: |
| 摘要 目的：研究C 反应蛋白（C-reactive protein，CRP）、降钙素原（Procalcitonin，PCT）以及白细胞（White blood cell，WBC）联合检测对中老年社区获得性肺炎患者的诊断效果。方法：选择2018年1月～2019年1月我院收治的76例中老年社区获得性肺炎患者为观察组，同期在我院体检中心选取30例健康体检者为对照组。检测两组研究对象的CRP、PCT及WBC水平 。采取肺炎严重程度 CURB-65评分将观察组的76例患者分为低危组（n=63例），CURB-65评分＜3分，以及高危组（n=13例），CURB-65评分≥3分；依照观察组的转归情况分为存活组（n=70例）以及死亡组（n=6例），比较观察组和对照组患者，低危组和高危组患者，存活组和死亡组患者的CRP、PCT及WBC水平的差异。结果：观察组患者的CRP、PCT及WBC水平明显高于对照组（P<0.05）；高危组患者的CRP、PCT水平明显高于低危组患者（P<0.05），而WBC水平两组无明显差异（P>0.05）；死亡组患者的CRP、PCT水平明显高于存活组患者（P<0.05），而WBC水平两组无明显差异（P>0.05）。经Pearson相关分析发现，CURB-65评分与PCT、CRP均呈明显的正相关（t=0.532，0.497，P均<0.05）。结论：CRP、PCT以及联合检测可以为中老年社区获得性肺炎的诊断提供有利的信息，且CRP、PCT与患者的病情严重程度有一定的相关性。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the diagnostic efficacy of combined detection of C-reactive protein (CRP), procalcitonin (PCT) and white blood cell (WBC) in elderly patients with community acquired pneumonia. Methods: Selected 76 cases of elderly patients with community acquired pneumonia who were treated in our hospital from January 2018 to January 2019 as observation group. In the same period, 30 healthy people in our physical examination center were selected as the control group. The levels of CRP, PCT and WBC in the two groups were detected. The CURB-65 score of pneumonia was used to classify 76 patients in the observation group into low-risk group (n=63 cases), CURB-65 score <3 points, and high-risk group (n=13 cases), CURB-65 score ≥3 points; according to the outcome of the observation group, the survival group (n=70 cases) and the death group (n=6 cases), the comparison observation group and the control group, the low-risk group and the high-risk group, the survival group and the death group. Differences in CRP, PCT and WBC levels in the group. Results: The CRP, PCT and WBC levels in the observation group were significantly higher than control group (P<0.05). The levels of CRP and PCT in the high-risk group were significantly higher than those in the low-risk group (P<0.05), but there was no significant difference between the two groups (P>0.05). The CRP and PCT levels in the death group were significantly higher than those in the surviving group(P<0.05), but there was no significant difference between the two groups (P>0.05). Pearson correlation analysis showed that CURB-65 score was positively correlated with PCT and CRP (t=0.532, 0.497, P<0.05). Conclusion: The combined detection of CRP and PCT can provide useful information for the diagnosis of community-acquired pneumonia in the elderly, and has a certain correlation with the severity of the disease. |
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