| 符小玲,蔡兴权,徐春柳,夏子雯,夏 兰.191例成分输血不良反应的调查分析[J].现代生物医学进展英文版,2020,(9):1769-1772. |
| 191例成分输血不良反应的调查分析 |
| Investigation and Analysis of 191 Cases of Adverse Reactions in the Component Blood Transfusion |
| Received:September 23, 2019 Revised:October 18, 2019 |
| DOI：10.13241/j.cnki.pmb.2020.09.037 |
| 中文关键词: 成分输血 不良反应 单采血小板 冰冻血浆 红细胞悬液 |
| 英文关键词: Component blood transfusion Adverse reactions Apheresis platelets Frozen plasma Suspension of red blood cells |
| 基金项目:海南省自然科学基金指导项目（806113） |
| Author Name | Affiliation | E-mail | | FU Xiao-ling | Department of blood transfusion of Hainan maternal and child health hospital, Haikou, Hainan, 570206, China | fuxiaoling88@126.com | | CAI Xing-quan | Department of blood transfusion of People's Hospital of Hainan Province, Haikou, Hainan, 570311, China | | | XU Chun-liu | Department of blood transfusion of People's Hospital of Hainan Province, Haikou, Hainan, 570311, China | | | XIA Zi-wen | Department of blood transfusion of People's Hospital of Hainan Province, Haikou, Hainan, 570311, China | | | XIA Lan | Department of blood transfusion of People's Hospital of Hainan Province, Haikou, Hainan, 570311, China | |
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| 中文摘要: |
| 摘要 目的：探讨成分输血不良反应的发生情况和原因，并总结其预防和处理措施。方法：回顾性分析2014年1月～2017年12月在海南省人民医院输注成分血的65300例病人的临床资料和输血不良反应回报单，统计后者的相关状况，并分析导致不良反应的原因，总结预防和处理措施。结果：65300例输注成分血的患者中，191例患者发生输血不良反应，总发生率为0.29%，以过敏反应(53.4%)和发热性非溶血性输血反应(34.0%)为主，其它占12.6%。血液成分输注发生不良反应以单采血小板最高(0.46%)，其次为冰冻血浆(0.35%)，红细胞悬液和冷沉淀分别为(0.21%)和(0.17%)。与红细胞悬液相比，冰冻血浆输血不良反应的发生率明显增高(P＜0.01)；与红细胞悬液和冰冻血浆相比，单采血小板输血不良反应发生率明显增高(P＜0.01)。此外，随着输血次数的增加，输血不良反应的发生率明显升高(P＜0.01)。结论：近年来，海南省人民医院因成分输血所致不良反应大部分源于过敏反应及发热性非溶血性输血反应，其中发生率最高的是单采血小板输血不良反应。临床医务人员需仔细把控输血指征，选择合适的血液成分，认真执行输血操作规程，以降低输血反应，保障输血安全。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the incidence and cause of adverse reactions in the component blood transfusion, and summarize corresponding preventive measures and treatment. Methods: The clinical data and report form of adverse transfusion reactions of 65300 cases of patients with component blood transfusion who were treated in the People's Hospital of Hainan Province were retrospectively analyzed. The incidence, causes and treatment of adverse transfusion reactions were analyzed. Results: Of 65300 cases of patients with component blood transfusion, adverse transfusion reactions were found in 191 cases, the total incidence was 0.29%, mainly anaphylactic reactions(53.4%) and non hemolytic febrile transfusion reactions(34.0%), other adverse transfusion reactions accounted for 12.6%. The incidence of adverse reactions in apheresis platelets transfusion was the highest(0.46%), followed by frozen plasma (0.35%),suspension and Cryoprecipitate of red blood cells(0.21% and 0.17%). Compared with suspension of red blood cells, the incidence of adverse transfusion reactions in frozen plasma was obviously higer, and compared with the suspension and Cryoprecipitate of red blood cells(P＜0.01), the incidence of adverse transfusion reactions in apheresis platelets was obertly highe (P＜0.01). In addition, with the increase of transfusion times, the incidence of adverse transfusion reactions was gradually elevated(P＜0.01). Conclusion: In recent years, the incidence of adverse reactions in component blood transfusion in the People's Hospital of Hainan Province was highest in apheresis platelets transfusion, which was mainly characterized as anaphylactic reactions and non hemolytic febrile transfusion reactions. Clinical medical personnel should strictly master the transfusion indications, choose appropriate blood component and obey the Blood transfusion protocol so as to decrease the adverse transfusion reactions. |
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