| 邹应芬,崔玉宝,吕 蓓,叶 佳,贾浩源,马锦琪.妇科盆腔恶性肿瘤血常规检测结果分析[J].现代生物医学进展英文版,2020,(8):1569-1574. |
| 妇科盆腔恶性肿瘤血常规检测结果分析 |
| Routine Blood Test in Pelvic Malignant Tumors |
| Received:October 23, 2019 Revised:November 18, 2019 |
| DOI：10.13241/j.cnki.pmb.2020.08.038 |
| 中文关键词: 血常规 恶性肿瘤 诊断 |
| 英文关键词: Routine Blood Test Malignant tumors Diagnosis |
| 基金项目:无锡市卫生计生委科研项目（Q201709）；江苏省重点研发(社会发展)计划项目（BE2018627） |
| Author Name | Affiliation | E-mail | | ZOU Ying-fen | Department of gynecology and obstetrics, Wuxi People's Hospital, Affiliated to Nanjing Medical University, Wuxi, Jiangsu, 214023, China | zouyingfen@163.com | | CUI Yu-bao | Department of Laboratory Medicine, Wuxi People's Hospital, Affiliated to Nanjing Medical University, Wuxi, Jiangsu, 214023, China | | | LV Bei | Department of gynecology and obstetrics, Wuxi People's Hospital, Affiliated to Nanjing Medical University, Wuxi, Jiangsu, 214023, China | | | YE Jia | Department of gynecology and obstetrics, Wuxi People's Hospital, Affiliated to Nanjing Medical University, Wuxi, Jiangsu, 214023, China | | | JIA Hao-yuan | Department of Laboratory Medicine, Wuxi People's Hospital, Affiliated to Nanjing Medical University, Wuxi, Jiangsu, 214023, China | | | MA Jin-qi | Department of gynecology and obstetrics, Wuxi People's Hospital, Affiliated to Nanjing Medical University, Wuxi, Jiangsu, 214023, China | |
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| 中文摘要: |
| 摘要 目的：了解妇科盆腔恶性肿瘤血常规变化及其临床意义。方法：以无锡市人民医院2018年1月~2019年3月收治的90例妇科盆腔恶性肿瘤患者作为病例组，同期住院的243例确诊为盆腔良性病变或妊娠状态的患者作为良性对照组，选取同期717名接受体检的成年女性作为健康对照组，对三组研究对象的血常规指标进行回顾性分析。结果：与健康对照组比较，良性对照组和病例组患者的嗜酸性粒细胞百分比（EO）、嗜酸性粒细胞计数（EO#）、红细胞压积（HCT）、血红蛋白水平（HGB）、淋巴细胞百分比（LY）、淋巴细胞计数（LY#）、红细胞平均血红蛋白浓度（MCHC）、血小板分布宽度（PDW）、红细胞计数（RBC）水平降低，单核细胞计数（MO#）、血小板平均体积（MPV）、中性粒细胞百分比（NE）、中性粒细胞计数（NE#）、红细胞分布宽度（RDW）、白细胞计数（WBC）水平升高；病例组患者EO、EO#、LY、LY#、MO#、MPV水平低于良性对照组，HCT、HBG、MCHC、PDW、NE、NE#、RDW水平高于良性对照组，同时，病例组患者的红细胞平均血红蛋白含量（MCH）、红细胞平均体积（MCV）水平高于健康对照组，健康对照组的MCH、MCV水平高于良性对照组，良性对照组患者的单核细胞百分比（MO）、血小板压积（PCT）水平高于健康对照组，健康对照组的MO、PCT水平高于病例组，差异均有统计学意义（P<0.05）。Logistic多元回归分析结果显示，LY#、MO#、MCHC、RDW、MCH、MCV与盆腔恶性肿瘤的发生具有相关性（P<0.05）。ROC曲线分析结果显示，在各项血常规指标中，MCV诊断妇产科盆腔恶性肿瘤的曲线下面积（AUC）最高，为0.683。结论：盆腔恶性肿瘤患者的血常规指标与良性病变患者和健康人群均存在差异，部分指标与恶性肿瘤的发生具有独立相关性。 |
| 英文摘要: |
| ABSTRACT Objective: To know the routine blood test in patients with pelvic malignant tumors. Methods: 90 patients with pelvic malignant tumors in the Department of gynecology and obstetrics from January of 2018 to March of 2019 were involved as the case group, 243 patients diagnosed as pelvic benign lesions or gestational status in the same period were treated as the benign control group, 717 adult women receiving physical examinations in the same period were selected as the healthy control group. The routine blood test results of the subjects in the three groups were analyzed and compared retrospectively. Results: Compared with the healthy control group, the eosinophil percentage (EO), the eosinophil count (EO), the hematocrit (HCT), the hemoglobin level (HGB), the lymphocyte percentage (LY), the lymphocyte count (LY), the mean hemoglobin concentration (MCHC), the platelet distribution width (PDW), the red blood cell count (RBC) decreased in the patients in the benign control group and the case group, while the mononuclear cell count (MO), the mean platelet volume (MPV), the neutrophil percentage (NE), the neutrophil count (NE), the red blood cell distribution width (RDW), the white blood cell count (WBC) levels increased. The levels of EO, EO#, LY, LY#，MO#, MPV of the patients in the case group were lower than those in the benign control group, while the levels of HCT, HBG, MC, PDW, NE, NE#, RDW were higher than those in the benign control group. Meanwhile, the mean content of hemoglobin (MCH) and the mean corpuscular volume (MCV) of the patients in the case group were higher than those in the healthy control group. The levels of MCH and MCV of the healthy control group were higher than those in the benign control group. The levels of MO and PCT of the benign control group were higher than those of the healthy control group and the healthy control group. The levels of monocyte percentage (MO) and platelet hematocrit (PCT) of the patients in the benign control group were higher than those in the healthy control group, the levels of MO and PCT of the subjects in the healthy control group were higher than those in the case group. The differences were statistically significant (P<0.05). Logistic multivariate regression analysis showed that LY, MO, MCHC, RDW, MCH, MCV were correlated with the occurrence of pelvic malignant tumors (P<0.05). The results of ROC curve analysis showed that the area under curve (AUC) of MCV in the diagnosis of pelvic malignant tumors was the highest, which was 0.683. Conclusion: There are clear differences in blood routine indexes among the patients with pelvic malignant tumors, the patients with pelvic benign lesions and the healthy people. Some indicators are independently correlated with the occurrence of malignant tumors and are expected to be used in assistant clinical diagnosis. |
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