| 王爱珠,王 宾,黄旴宁,王乐华,吴煌福.彩色多普勒超声应用于乳腺癌诊断及其新辅助化疗疗效评价的临床价值研究[J].现代生物医学进展英文版,2020,(4):768-771. |
| 彩色多普勒超声应用于乳腺癌诊断及其新辅助化疗疗效评价的临床价值研究 |
| Clinical Value of Color Doppler Ultrasound in Diagnosis of Breast Cancer and Evaluation of Efficacy of Neoadjuvant Chemotherapy |
| Received:September 07, 2019 Revised:September 30, 2019 |
| DOI：10.13241/j.cnki.pmb.2020.04.036 |
| 中文关键词: 彩色多普勒超声 乳腺癌 新辅助化疗 诊断 疗效 |
| 英文关键词: Color Doppler ultrasound Breast cancer Neoadjuvant chemotherapy Diagnosis Efficacy |
| 基金项目:海南省卫生计生行业科研项目（18A200017） |
| Author Name | Affiliation | E-mail | | WANG Ai-zhu | Department of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570311, China | wangaizhu189@sina.com | | WANG Bin | Department of Interventional Therapy, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570311, China | | | HUANG Xu-ning | Department of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570311, China | | | WANG Le-hua | Department of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570311, China | | | WU Huang-fu | Department of Surgical Oncology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570311, China | |
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| 中文摘要: |
| 摘要 目的：探讨彩色多普勒超声对乳腺良恶性肿瘤的鉴别诊断价值以及其对乳腺癌患者新辅助化疗疗效的评估价值。方法：选取2017年1月到2018年11月期间在我院接受治疗的乳腺癌患者88例作为乳腺癌组，另选取同期在我院接受治疗的乳腺良性肿瘤患者60例作为良性对照组，良性对照组在治疗前，乳腺癌患者在化疗前后采用彩色多普勒超声进行检查，记录所有患者的二维超声表现、彩色多普勒超声表现。结果：乳腺癌组的形态不规则、边界不清晰、内部回声不均匀、后方回声异常的比例均高于良性对照组，差异有统计学意义（P<0.05），两组患者的血流分级分布情况整体比较差异有统计学意义（P<0.05），乳腺癌组的血流阻力指数（RI）高于良性对照组（P<0.05）。化疗后，治疗有效组的乳腺肿瘤体积小于治疗无效组，治疗有效组的形态不规则、边界不清晰、内部回声不均匀、后方回声异常的比例低于治疗无效组（P<0.05），治疗有效组的血流分级分布情况及RI与治疗无效组比较差异亦有统计学意义（P<0.05）。结论：彩色多普勒超声对乳腺良恶性肿瘤具有较高的鉴别诊断价值，同时也可用于乳腺癌患者新辅助化疗疗效的评估。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the value of color Doppler ultrasonography in the differential diagnosis of benign and malignant breast tumors and its evaluation of the efficacy of neoadjuvant chemotherapy for breast cancer patients. Methods: 88 breast cancer patients who were treated in our hospital from January 2017 to November 2018 were selected as the breast cancer group. 60 patients with benign breast tumors who were treated in our hospital at the same time were selected as benign control group. In the benign control group, breast cancer patients were examined by color Doppler ultrasound before and after chemotherapy. The two-dimensional ultrasound findings and color Doppler ultrasound findings of all patients were recorded. Results: The proportions of the breast cancer group with irregular shape, unclear boundary, uneven internal echo and abnormal of the posterior echo were higher than those of the benign control group, the differences were statistically significant(P<0.05). There was significant difference in blood flow grading distribution between the two groups (P<0.05). The blood flow resistance index (RI) of the breast cancer group was higher than that of the benign control group(P<0.05). After chemotherapy, the tumor volume of the patients in the treatment-effective group was smaller than that of the treatment-ineffective group, the proportion of irregular shape, unclear boundary, uneven internal echo, and abnormal of the posterior echo in the treatment effective group were lower than those the treatment-ineffective group(P<0.05). There were also significant differences in blood flow grading distribution and RI between the effective group and the ineffective group(P<0.05). Conclusion: Color Doppler ultrasound has a high differential value in the differential diagnosis of benign and malignant breast tumors, and it also can be used to evaluate the efficacy of neoadjuvant chemotherapy in breast cancer patients. |
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