| 李 良,李 强,孙银娣,李亚峰,曹 毅.中药穴位贴敷联合硬膜外镇痛泵对老年髋关节骨折患者镇痛效果的影响[J].现代生物医学进展英文版,2019,19(23):4508-4511. |
| 中药穴位贴敷联合硬膜外镇痛泵对老年髋关节骨折患者镇痛效果的影响 |
| Effect of Traditional Chinese Medicine Acupoint Application Combined with Epidural Analgesia Pump on Analgesia in Elderly Patients with Hip Fracture |
| Received:June 05, 2019 Revised:June 30, 2019 |
| DOI：10.13241/j.cnki.pmb.2019.23.025 |
| 中文关键词: 中药穴位贴敷 硬膜外镇痛泵 髋关节骨折 镇痛效果 β-内啡肽 不良反应 |
| 英文关键词: Traditional Chinese medicine acupoint application Epidural analgesia pump Hip fracture Analgesic effect β-endorphin Adverse reactions |
| 基金项目:陕西省体育局科研基金项目（2018055） |
| Author Name | Affiliation | E-mail | | LI Liang | Department of Traditional Chinese Medicine, Xi'an Jiaotong University Affiliated Red Cross Hospital, Xi'an, Shaanxi, 710000, China | liliang198104@163.com | | LI Qiang | Department of Bone, Shaanxi Provincial Fourth People's Hospital, Xi'an, Shaanxi, 710000, China | | | SUN Yin-di | Department of Traditional Chinese Medicine, Xi'an Jiaotong University Affiliated Red Cross Hospital, Xi'an, Shaanxi, 710000, China | | | LI Ya-feng | Department of Traditional Chinese Medicine, Xi'an Jiaotong University Affiliated Red Cross Hospital, Xi'an, Shaanxi, 710000, China | | | CAO Yi | Department of Traditional Chinese Medicine, Xi'an Jiaotong University Affiliated Red Cross Hospital, Xi'an, Shaanxi, 710000, China | |
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| 中文摘要: |
| 摘要 目的：探讨中药穴位贴敷联合硬膜外镇痛泵对老年髋关节骨折患者镇痛效果的影响。方法：选取2012年2月至2019年2月西安交通大学附属红会医院中医骨科80例老年髋关节骨折患者为研究对象，根据入院顺序，随机化原则将受试者分为对照组和研究组，每组40例，对照组患者术后均给予硬膜外镇痛泵止痛，研究组患者在对照组的基础上联合中药穴位贴敷止痛，比较两组患者术后的疼痛程度、疼痛相关指标、手术前后血清β-内啡肽水平变化及术后镇痛不良反应发生率。结果：研究组患者在术后1 d、3 d、7 d静息状态及活动状态的近期视觉模拟评分(Visual analogue scale, VAS)均显著低于对照组（P＜0.05），研究组患者疼痛时间、爆发痛次数、术后24 h按压镇痛泵次数、睡眠时间及止痛剂用量均显著少于对照组（P<0.05），术后首次按压镇痛泵时间显著长于对照组（P<0.05），术前两组患者的血清?茁-内啡肽水平比较无统计学差异（P>0.05），术后24 h及48 h研究组患者的血清?茁-内啡肽水平均显著高于对照组（P＜0.05），两组术后镇痛不良反应发生率比较无统计学差异（P>0.05）。结论：中药穴位贴敷联合硬膜外镇痛泵可有效缓解术后疼痛，减少止痛剂用量，提高患者睡眠质量及血清?茁-内啡肽水平，对促进髋关节骨折患者术后康复具有积极意义。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the effect of acupoint sticking with traditional Chinese medicine combined with epidural analgesia pump on analgesia in elderly patients with hip fracture. Methods: 80 elderly patients with hip fracture were selected as research object from February 2012 to February 2019. According to the principle of randomization, the subjects were divided into the control group and the study group and each group of 40 cases. The control group received an epidural analgesia pump for pain relief after surgery, the study group on the basis of this combination of traditional Chinese medicine acupoint application. Postoperative pain, various pain-related indicators, changes in serum β-endorphin levels before and after surgery, and incidence of postoperative analgesia were compared for the two groups. Results: The VAS scores of the study group at 1d, 3d, 7d after resting and active status were significantly lower than the control group(P<0.05). The pain time, number of outbreaks, pressing the analgesic pump frequency at 24 hours after surgery, sleeping time and analgesic dosage in the study group were significantly lower than those in the control group(P<0.05). The time of first press of analgesia pump postoperative was significantly longer than that of the control group(P<0.05). There was no significant difference in serum β-endorphin levels between the two groups before surgery(P>0.05). The serum β-endorphin levels in the study group were significantly higher than those in the control group at 24 h and 48 h after surgery(P<0.05). There was no significant difference in the incidence of postoperative analgesic adverse reactions between the two groups(P>0.05). Conclusion: Traditional Chinese medicine acupoint application combined with epidural analgesia pump can effectively relieve postoperative pain, reduce the dosage of analgesics, improve the quality of sleeping and serum β-endorphin level, which has positive significance for promoting postoperative rehabilitation of patients with hip fracture. |
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