| 武志贤,丁 钰,杜 莉,曹伟靖,田 莹,高朵朵,付 蓉.牙周超声治疗仪联合头孢克洛治疗牙周炎的临床研究[J].现代生物医学进展英文版,2019,19(19):3734-3737. |
| 牙周超声治疗仪联合头孢克洛治疗牙周炎的临床研究 |
| A Clinical Study on the Periodontal Ultrasound Therapy Combined with Cefaclor in the Treatment of Periodontitis |
| Received:January 28, 2019 Revised:February 23, 2019 |
| DOI：10.13241/j.cnki.pmb.2019.19.031 |
| 中文关键词: 牙周超声治疗仪 头孢克洛 牙周炎 白细胞介素-1β 肿瘤坏死因子-α |
| 英文关键词: Periodontal ultrasound therapeutic instrument Cefaclor Periodontitis IL-1β TNF- α |
| 基金项目:国家自然科学基金青年科学基金项目(81700986) |
| Author Name | Affiliation | E-mail | | WU Zhi-xian | Oral medicine department, Stomatological Hospital Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, 716000, China | wuzhixian93@163.com | | DING Yu | Stomatology department, Baoji Traditional Chinese Medicine Hospital, Baoji, Shaanxi, 721000, China | | | DU Li | Oral medicine department, Stomatological Hospital Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, 716000, China | | | CAO Wei-jing | Oral medicine department, Stomatological Hospital Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, 716000, China | | | TIAN Ying | Oral medicine department, Stomatological Hospital Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, 716000, China | | | GAO Duo-duo | Oral medicine department, Stomatological Hospital Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, 716000, China | | | FU Rong | Oral medicine department, Stomatological Hospital Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, 716000, China | |
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| 中文摘要: |
| 摘要 目的：研究牙周超声治疗仪联合头孢克洛治疗牙周炎患者的临床效果。方法：选择2016年1月～2018年6月我院收治的70例牙周炎患者，共有患牙103颗，将其随机分为两组。对照组采用牙周超声治疗仪治疗，观察组在牙周超声治疗后联合口服头孢克洛，每次0.25 g，每8 h给药1次。比较两组治疗前后的咬合指标(咬合创伤指数(TOI)和咬合时间(OT))、牙周指标(附着水平(AL)、探诊深度(PD)、临床附着丧失(CAL)和出血指数(BI))、血清炎性指标(白细胞介素-1β(IL-1β)和肿瘤坏死因子-α(TNF-α))水平的改变情况。结果：治疗后，观察组的有效率明显高于对照组(91.43% vs. 74.28%，P<0.05)；两组治疗后的TOI、OT、AL、PD、CAL、BI、血清IL-1β和TNF-α水平均较治疗前明显降低(P<0.05)，且观察组以上指标均明显低于对照组(P<0.05)。结论：牙周超声治疗仪联合头孢克洛治疗牙周炎患者的疗效，明显优于单用牙周超声治疗仪治疗，其可有效改善患者的牙周状况和咬合指标，并且能减轻炎症反应。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of periodontal ultrasound therapy combined with cefaclor in the treatment of periodontitis. Methods: 70 cases of patients with periodontitis who were treated in our hospital from January 2016 to June 2018 were selected and randomly divided into two groups. The control group was treated with periodontal ultrasound therapy instrument. The observation group was treated with oral cefaclor after periodontal ultrasound treatment, 0.25 g each time, once every 8 hours. The occlusal index (TOI) and occlusal time(OT), periodontal index(AL), probing depth(PD), clinical attachment loss(CAL), hemorrhagic index (BI), serum inflammatory index(IL-1beta) and tumor necrosis factor-alpha(TNF-alpha) were compared between the two groups before and after treatment. Results: After treatment, the effective rate of observation group was significantly higher than that of the control group (91.43% vs. 74.28%, P<0.05), the levels of TOI, OT, AL, PD, CAL, BI, serum IL-1beta and TNF-α in both groups were significantly lower than those before treatment(P<0.05), and the above indexes in the observation group were significantly lower than those in the control group (P<0.05). Conclusion: The curative effect of periodontal ultrasound therapy combined with cefaclor in the treatment of periodontitis is obviously better than that of periodontal ultrasound therapy alone. It can effectively improve the periodontal condition and occlusal index of patients, and relieve the inflammatory response. |
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