| 李路路,张希玲,王 岩,胡思宁,贾海波,于 波.不同性别急性心肌梗死合并心衰患者院内治疗及一年随访情况的比较[J].现代生物医学进展英文版,2019,19(12):2295-2298. |
| 不同性别急性心肌梗死合并心衰患者院内治疗及一年随访情况的比较 |
| A Comparison of the in-hospital Treatment and One-year Follow-up Cardiovascular Event between Male and Female Acute Myocardial Infarction Patients Combined with Heart Failure |
| Received:February 25, 2019 Revised:March 18, 2019 |
| DOI：10.13241/j.cnki.pmb.2019.12.020 |
| 中文关键词: 急性心肌梗死 性别 心衰 |
| 英文关键词: Acute Myocardial Infarction /AMI Gender Heart Failure |
| 基金项目:国家重点研发计划资助(2016YFC1301100) |
| Author Name | Affiliation | E-mail | | LI Lu-lu | 1 The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China
2 Key Laboratory of Myocardial Ischemia, Harbin, Heilongjiang, 150001, China | lulu1039415152@163.com | | ZHANG Xi-ling | 1 The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China
2 Key Laboratory of Myocardial Ischemia, Harbin, Heilongjiang, 150001, China | | | WANG Yan | 1 The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China
2 Key Laboratory of Myocardial Ischemia, Harbin, Heilongjiang, 150001, China | | | HU Si-ning | 1 The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China
2 Key Laboratory of Myocardial Ischemia, Harbin, Heilongjiang, 150001, China | | | JIA Hai-bo | 1 The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China
2 Key Laboratory of Myocardial Ischemia, Harbin, Heilongjiang, 150001, China | | | YU Bo | 1 The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China
2 Key Laboratory of Myocardial Ischemia, Harbin, Heilongjiang, 150001, China | |
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| 中文摘要: |
| 摘要 目的：比较不同性别急性心肌梗死(Acute Myocardial Infarction，AMI)合并心衰患者住院期间院内治疗方式、一年随访用药依从性及心血管不良事件发生情况。方法：收集我院2014年10月至2015年6月收治的136例急性心肌梗死合并心衰患者，分析和比较不同性别患者入院时的临床特征、住院期间治疗方式、一年随访过程中用药依从性以及心血管不良事件发生率的差异。结果：本研究共入组136例急性心肌梗死合并心衰患者，其中男性患者70(51.47 %)例，女性66(48.53 %)例。男性患者具有吸烟史、饮酒史的比例显著高于女性患者(62.86 % vs 28.79 %，P=0.001；35.71 % vs 10.61 %，P=0.001)，但具有糖尿病史的比例明显低于女性(35.71 % vs 53.03 %，P=0.042)；男性患者住院期间接受溶栓或经皮冠状动脉介入(Percutaneous Coronary Intervention，PCI)治疗的比例明显高于女性(62.86 % vs 45.45 %，P=0.042)；男性患者一年随访期间出现胸痛、卒中的比例低于女性(11.43 % vs 24.24 %，P=0.050；2.86 % vs 12.12 %，P=0.050)；但出血事件的发生率高于女性(10.00 % vs 0 %，P=0.014)。结论：男性急性心肌梗死合并心衰患者住院期间接受溶栓或PCI治疗的比例明显高于女性；一年随访过程中出现胸痛、卒中事件率低于女性，但出血事件的发生率高于女性。 |
| 英文摘要: |
| ABSTRACT Objective: To identify the difference of in-hospital treatments and one-year follow-up cardiovascular event rate between male and female acute Myocardial Infarction(AMI) patients combined with heart failure. Methods: 136 cases of AMI patients combined with heart failure from the Second Affiliated Hospital of Harbin Medical University were selected, including 70 (51.47 %) cases of male, and 66 cases of (48.53 %) female. The difference in the clinical characteristics, in-hospital treatment, follow-up medication compliance, and incidence rate of cardiovascular events were compared between male and female. Results: It was found that there were more smoking, drinking patients in male compared with female (62.86 % vs 28.79 %, P=0.001; 35.71 % vs 10.61 %, P=0.001), and less diabetes mellitus (DM) (35.71 %，vs 53.03 %, P=0.042). For in-hospital treatment, male tended to have more patients (62.86 % vs 45.45 %, P=0.042) to take thrombolytic or PCI therapy. Less chest pain, stoke happened in male (11.43 % vs 24.24 %, P=0.050; 2.86 % vs 12.12 %, P=0.050), and more bleeding (10.00 % vs 0 %, P=0.014) in male during one-year follow-up period. Conclusion: For AMI patients with heart failure, more male takes thrombolytic or PCI therapy, they have higher incidence rate of bleeding, lower incidence rate of chest pain and stroke during one-year follow-up period. |
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