| 吕成坚,肖 辉,李 群.快速现场细胞学评价在经支气管针吸活检术诊断肺部良恶性疾病的临床应用[J].现代生物医学进展英文版,2019,19(9):1670-1674. |
| 快速现场细胞学评价在经支气管针吸活检术诊断肺部良恶性疾病的临床应用 |
| Clinical Application of Rapid on-site Cytological Evaluation in Diagnosis of Lung Disease of EBUS-TBNA |
| Received:January 08, 2019 Revised:January 30, 2019 |
| DOI：10.13241/j.cnki.pmb.2019.09.014 |
| 中文关键词: 快速现场细胞学评价 超声引导下的经支气管针吸活检术 肺部良恶性疾病 |
| 英文关键词: C-ROSE EBUS-TBNA Lung disease |
| 基金项目:国家自然科学基金青年科学基金项目（81701547）；上海市松江区科学技术攻关项目（2017sjkjgg60）；北京医卫健康公益基金会项目（YWJKJJHKYJJ-F2187E） |
| Author Name | Affiliation | E-mail | | LV Cheng-jian | Department of Respiratory and Critical Medicine, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, 200080, China | lvtty@163.com | | XIAO Hui | Department of Respiratory and Critical Medicine, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, 200080, China | | | LI Qun | Department of Respiratory and Critical Medicine, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, 200080, China | |
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| 中文摘要: |
| 摘要 目的：超声引导下的经支气管针吸活检术(Endobronchial ultrasound guided transbronchial needle aspiration, EBUS-TBNA)是临床上广泛开展的经支气管的微创介入技术，在EBUS-TBNA过程中，快速现场细胞学评价(Cytological rapid on-site evaluation，C-ROSE)是切实可行的临床辅助技术。本研究探讨C-ROSE在EBUS-TBNA对肺部疾病诊断的细胞学特点及诊断价值。方法：对41例经胸部计算机断层扫描(Computed tomography，CT)发现存在纵隔和(或)肺门病灶(包括肿大的淋巴结／肿块)而行EBUS-TBNA及C-ROSE患者进行回顾性分析。结果：C-ROSE镜下的细胞学具有明显特点，对肺部良恶性疾病的穿刺成功率无差异，诊断率分别为90.48 %和66.67 %(P<0.05)，且C-ROSE可完全排除恶性疾病的诊断，二组并发症发生率分别为9.52 %和6.67 %(P<0.05)。结论：C-ROSE在EBUS-TBNA中对肺部良恶性病变均具有诊断价值，可以提高穿刺成功率及诊断率、减少并发症，值得在临床医疗介入中心推广。 |
| 英文摘要: |
| ABSTRACT Objective: Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) is a clinically widely performed minimally invasive interventional technique under the bronchi. In the EBUS-TBNA process, cytological rapid on-site evaluation (C-ROSE) is a practical clinical assistive technique. This study investigated the value of C-ROSE in the diagnosis of pulmonary disease by EBUS-TBNA. Methods: A retrospective analysis of 41 patients with EBUS-TBNA and C-ROSE who underwent computed tomogra- phy (CT) with mediastinal and/or hilar lesions (including enlarged lymph nodes/lumps) was performed. Results: The cytology under C-ROSE had obvious characteristics. There was no difference in the success rate of puncture of benign and malignant lung diseases. The diagnostic rates were 90.48% and 66.67%, respectively (P<0.05), and the diagnosis of C-ROSE in malignant diseases can be completely excluded. Furthermore, the complication rates of groups are 9.52% and 6.67%, respectively (P<0.05). Conclusion: C-ROSE has diagnos- tic value for benign and malignant lung diseases in EBUS-TBNA, which can improve the success rate of puncture and diagnosis rate and reduce complications. It is worthy of push in the medical center. |
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